In the Hilbert space formulation of classical mechanics, pioneered by Koopman and von Neumann, there are potentially more observables than in the standard approach to classical mechanics. In this Letter, we show that actually many of those extra observables are not invariant under a set of universal local symmetries which appear once the Koopman and von Neumann formulation is extended to includ...

— The paper shows that the current view of globalization as an automatic and benign force is flawed: it focuses on only one, positive, face of globalization while entirely neglecting the malignant one. The two key historical episodes that are adduced by the supporters of the ‘‘globalization as it is’’ (the Halcyon days of the 1870–1913, and the record of the last two decades of development) are...

Actinomyces spp. are considered rare pathogens in today's medicine, especially with thoracic vertebral involvement. Classic actinomycosis (50%) presents as an oral-cervicofacial ("lumpy jaw") infection. This report describes a case of spinal cord compression caused by Actinomyces israelii with the coisolation of Fusobacterium nucleatum. There are limited numbers of similar cases.

Improvements in technology and manufacturing reduce prices for sensing technology and allow the internet-connection of more and more base stations; therefore growing both the scale and application areas for wireless sensor networks. Reconfigurable, general purpose networks are replacing classic black-box sensor technology in the fields of environmental observations, for example conservation and...

OBJECTIVE To assess the conferred value and average cost-utility (cost-effectiveness) for intravitreal ranibizumab used to treat occult/minimally classic subfoveal choroidal neovascularization associated with age-related macular degeneration (AMD). DESIGN Value-based medicine cost-utility analysis. PARTICIPANTS MARINA (Minimally Classic/Occult Trial of the Anti-Vascular Endothelial Growth F...

A 42-year-old man with history of esophageal strictures and esophageal dilation presented to the emergency department with 12 hours of dysphagia and non-bloody emesis. His symptoms started upon waking and included sharp retrosternal pain during each attempt at swallowing. Dysphagia occurred with both solids and liquid. He denied difficulty initiating swallowing, pain with eating the previous ni...

This second approach to the doctrine and thinking of Edmund D. Pellegrino presents the basics of the author's proposal to reform medical ethics, based on the rehabilitation of beneficence principle in health care. It describes the research and interest of our bioethicist towards the concept of 'good' of the patient and his four components. Pellegrino's classic concepts of 'healing' and 'help' a...

Modern critical care medicine is marked by a steadily growing amount of available patient data. This causes a new challenge extracting significant information concerning the patient's prognosis or diagnosis. Classic approaches of the decision support are prognostic scoring systems like the APACHE Scoring System [1]. This paper discusses automatic generation of risk classifications. Three mayor ...