The strategies available for treating salivary gland hypofunction are limited because relatively little is known about the secretion process in humans. An initial microarray screen detected ion transport proteins generally accepted to be critically involved in salivation. We tested for the activity of some of these proteins, as well as for specific cell properties required to support fluid secr...

The wealth of information that has emerged in recent years detailing the substrate specificity of hepatic transporters necessitates an investigation into their potential role in drug elimination. Therefore, an assay in which the loss of parent compound from the incubation medium into hepatocytes ("media loss" assay) was developed to assess the impact of hepatic uptake on unbound drug intrinsic ...

This paper describes experiments on Cl transport into the roots, stem and leaves of bean plants, the roots of which have been exposed to lipids in the root solution. Monoand digalactose diglyceride strongly increased Cl transport into all plant parts, probably by transport of the glycolipids further into the plant. Phosphatidyl choline increased Cl absorption by the roots, but transport into th...

OBJECTIVE To test the frictional resistance forces (FRS) generated between several archwires and (1) interactive self-ligating (ISL) brackets and (2) conventionally ligated (CL) brackets. MATERIALS AND METHODS Frictional forces produced between three different archwire combinations and self-ligating (SL) brackets (ceramic and metal-slot or all-metal) and CL brackets (metal or ceramic) were ev...

Cooperation logics have recently begun to attract attention within the multi-agent systems community. Using a cooperation logic, it is possible to represent and reason about the strategic powers of agents and coalitions of agents in game-like multi-agent systems. These powers are generally assumed to be implicitly defined within the structure of the environment, and their origin is rarely discu...

Oriented films of the sodium salt of heparin crystallize in a triclinic unit cell. The X-ray diffraction results favour a tetrasaccharide covalent repeating sequence but the measured molecularrepeat of1.59nm is inconsistent with all a-(1 -*4)(lax -->4eq)-glycosidic linkages as generally accepted. Three models are proposed for the molecular shape of heparin, which depend on the chair conformatio...

Methylisothiocyanate The fumigants were introduced into 2.54-cm-diameter holes at timber midlength. Fumigants diffused throughout the cross-sectional area of both southern pine and Douglas-fir. The brownand white-rot fungi generally showed similar tolerance to the fumigants. Chloropicrin killed most fungal cultures in both tim­ bers 0.30 in from the treatment centerline (CL) within 1 week after...

Adsorbable organic halides (AOX) and AOX formation potential (AOXFP) were investigated in 46 landfill lea-chates as potentially toxic parameters. AOX in landfill leachate was within the range <10–2200 mg Cl/l, and AOXFP was within 51–15 000 mg Cl/l. AOX and AOXFP correlated with chemical oxygen demand (COD).AOX discharge from closed landfills was generally lower than that from operating landfil...

Experiments using Na-uptake and serial sampling techniques showed that during dehydration Na was taken up by the fat body in adult Periplaneta americana, but not in nymphs. Generally, accumulation of Na in the fat body was highest in animals which had little reserve lipid and in those which excreted the smallest amounts of Na during the dehydration period. Dehydration caused little change in th...