BACKGROUNDS/AIMS Prognostic factors for colorectal cancer with hepatic metastasis are not well-established. We investigated the factors that predicted survival following surgical resection of hepatic metastases in patients with colorectal cancer. METHODS Fifty-three patients underwent resection of hepatic metastases of colorectal cancer between January 2000 and December 2005, with follow-up p...

Human placental alkaline phosphatase (HPLAP), carcinoembryonic antigen (CEA), and cancer antigen 125 (CA 125) were localized immunohistochemically in paraffin sections of normal lung tissue from 16 patients, using monoclonal antibodies and an indirect avidin-biotin-peroxidase staining procedure. HPLAP and CEA were present in epithelial cells of respiratory bronchioli and alveolar type I pneumoc...

ach are extremely rare, accounting for less than 0.1% of primary gastric cancers [1]. The clinical behavior of primary gastric small cell carcinoma is as aggressive as that of small lung cancer [2]. Distal metastases are frequentlyobserved at initial presentation [3]. Small cell carcinomas proliferates mainly in the submucosal layer like a carcinoid tumor [1,4]; however, the tumor may have endo...

A panel of three monoclonal antibodies were used in an immunoalkaline phosphatase staining method on a series of serous effusion samples from cases of mesothelioma, lung carcinoma, and benign disease. The antibodies used were anti-carcinoembryonic (CEA) antigen, Ca, and anti-human milk fat globule membrane antigen. Antibodies to the Ca antigen and human milk fat globule membrane antigen stained...

coincidental occurrence of hepatocellular carcinoma (hcc) and cholangiocarcinoma, known as “collision tumors”, within a cirrhotic liver is rare. herein, we report a case of liver transplantation (lt) in a patient with such collision tumors. our patient was a 56-year-old woman with hepatitis c virus-related cirrhosis and 2 focal hepatic lesions, measuring 1.5 and 3 cm, in the liver segments 8 an...

Recently, several cases of intraductal oncocytic papillary neoplasm (IOPN) of the liver and hepatic bile ducts have been reported. The author herein reports the first case of IOPN of the common bile duct (CBD). A 78-year-old man was admitted to our hospital because of jaundice. Imaging modalities including US, CT, MRI revealed an intraductal tumor of the middle CBD and biliary dilation distal t...

CDH17 stained 100% (99/99) of colon adenocarcinoma, whereas CK20 and CDX2 stained 92% (91/99) and 96% (95/99), respectively (Figure 1A-C and Figure 2A-C). In stomach adenocarcinoma, CDH17 stained 73% (50/69), CK20 28% (19/69) and CDX2 16% (11/69) (Figure 3A-C) (Table 1). CDH17 was positive in 35% (10/29) of pancreatic ductal cell adenocarcinomas (Figure 4A) (data not shown). All cases of pancre...

Background: Flat urothelial lesions comprise a spectrum of morphologic changes ranging from reactive atypia to carcinoma in situ (CIS). Urothelial dysplasia and CIS are associated with the recurrence and progression of urothelial carcinoma. Distinguishing CIS and dysplasia from reactive atypia based on histolopathogical features alone is often difficult. Using different immunohistochemical mark...