epithelium with regular basally located nuclei and without atypia or mitotic activity (Figure C). There were no pancreatic acini or islets. We did not observe Paneth cells or goblet cells. immunohistochemistry was performed using antibodies against CK7 (OV-tL 2/30, neomarkers, CA, usA : 50), sMA ( A4, :300 neomarkers, CA, usA) and CK20 (Ks20.8, : 00 neomarkers, CA, usA). immunohistochemistry re...

Invasive urothelial carcinoma is the most common bladder malignancy, comprising 90% of all primary carcinomas. According to statistics Georgia, according NCDC data, cancer third among men. As a result non-invasive carcinoma, 70% operated patients developed recurrence in 5-year period after surgical intervention on urinary bladder, which share advanced, metastatic cases 10-20%.Therefore, regardl...

Background: Colorectal carcinoma is a malignant epithelial tumor originating in the large bowel. More than 90% of colorectal carcinomas (CRC) are adenocarcinomas. This being graded morphologically at H&E stain histopathology as well-differentiated, moderately differentiated, and poorly differentiated. Aims Objectives: The aim this study to assess any association with different histopatholog...

background: flat urothelial lesions comprise a spectrum of morphologic changes ranging from reactive atypia to carcinoma in situ (cis). urothelial dysplasia and cis are associated with the recurrence and progression of urothelial carcinoma. distinguishing cis and dysplasia from reactive atypia based on histolopathogical features alone is often difficult. using different immunohistochemical mark...

BACKGROUND Endometrial adenocarcinomas are a rare type of tumour in cats. Though different morphologies have been reported, the most frequent histological type of feline endometrial adenocarcinoma (FEA) is the papillary serous. Characterization of molecular markers expression in FEA may contribute to clarify the pathogenesis of these tumours and to assess the differences between normal endometr...

Background: Flat urothelial lesions comprise a spectrum of morphologic changes ranging from reactive atypia to carcinoma in situ (CIS). Urothelial dysplasia and CIS are associated with the recurrence and progression of urothelial carcinoma. Distinguishing CIS and dysplasia from reactive atypia based on histolopathogical features alone is often difficult. Using different immunohistochemical mark...

We studied the diagnostic value of Cdx2 to distinguish mucinous bronchioloalveolar carcinoma from mucinous colorectal adenocarcinoma metastatic to the lung. We retrieved 92 via the hospital computer system, including 30 mucinous bronchioloalveolar carcinomas, 32 nonmucinous bronchioloalveolar carcinomas, and 30 mucinous colorectal adenocarcinomas metastatic to the lung. All cases were confirmed...

BACKGROUND AND AIMS Cytokeratin (CK) 7 and 20 patterns are specific for long and short segments of Barrett's oesophagus but their use has not been assessed in intestinal metaplasia arising in macroscopically normal gastro-oesophageal junction (GOJ). PATIENTS AND METHODS This study was carried out in a large prospective series of 254 patients who underwent upper endoscopy, had normal gastro-oe...

BACKGROUND We assessed the expression of cytokeratin (CK) and apomucin (MUC) in ampullary carcinoma (AC) to develop a system for the classification of ACs on the basis of their clinical significance. METHOD We studied the expressions of CK7, CK20, MUC1, MUC2, MUC5AC, and MUC6 in 43 patients with ACs. Clinical data were obtained retrospectively by examining surgically resected ACs of the patie...