نتایج جستجو برای: circadian variation

تعداد نتایج: 319046  

Journal: :Journal of Clinical Neuroscience 2006

2017
Shuo-wen Chang Toshinori Yoshihara Shuichi Machida Hisashi Naito

Intracellular signaling exhibits circadian variation in the suprachiasmatic nucleus and liver. However, it is unclear whether circadian regulation also extends to intracellular signaling pathways in the cardiac and skeletal muscles. Here, we examined circadian variation in the intracellular mammalian target of rapamycin (mTOR)/70 kDa ribosomal protein S6 kinase 1 (p70S6K) and extracellular sign...

2013
Aline V Machado-Nils Larissa OM de Faria André S Vieira Simone A Teixeira Marcelo N Muscará Elenice AM Ferrari

BACKGROUND Nitric oxide synthase (NOS) is essential for the synthesis of nitric oxide (NO), a non-conventional neurotransmitter with an important role in synaptic plasticity underlying processes of hippocampus-dependent memory and in the regulation of biological clocks and circadian rhythms. Many studies have shown that both the NOS cytosolic protein content and its enzymatic activity present a...

Journal: :Proceedings of the National Academy of Sciences of the United States of America 2015
Qiguang Xie Ping Lou Victor Hermand Rashid Aman Hee Jin Park Dae-Jin Yun Woe Yeon Kim Matti Juhani Salmela Brent E Ewers Cynthia Weinig Sarah L Khan D Loring P Schaible C Robertson McClung

GIGANTEA (GI) was originally identified by a late-flowering mutant in Arabidopsis, but subsequently has been shown to act in circadian period determination, light inhibition of hypocotyl elongation, and responses to multiple abiotic stresses, including tolerance to high salt and cold (freezing) temperature. Genetic mapping and analysis of families of heterogeneous inbred lines showed that natur...

Journal: :Journal of the American College of Cardiology 2006
Wolfgang Poller Heinz-Peter Schultheiss Uwe Kühl

. Moreno PR, Fuster V. The year in atherothrombosis. J Am Coll Cardiol 2004;44:2099–110. . Muller JE, Stone PH, Turi ZG, et al. Circadian variation in the frequency of onset of acute myocardial infarction. N Engl J Med 1985; 313:1315–22. . Abo T, Kawate K, Itoh K, et al. Studies on the bioperiodicity of the immune response. Circadian rhythms of human T, B and K cell traffic in the peripheral bl...

Journal: :Plant, cell & environment 2016
Matti J Salmela Kathleen Greenham Ping Lou C Robertson McClung Brent E Ewers Cynthia Weinig

Circadian clocks have evolved independently in all three domains of life, and fitness benefits of a functional clock have been demonstrated in experimental genotypes in controlled conditions. Still, little is known about genetic variation in the clock and its fitness consequences in natural populations from heterogeneous environments. Using Wyoming populations of the Arabidopsis relative Boeche...

Journal: :Neuroscience letters 1991
R Mason

The circadian variation in neuronal discharge activity recorded in vitro from the Syrian hamster suprachiasmatic nucleus (SCN), identified as a circadian clock, was used as an index of SCN circadian function. SCN neurones (n = 89) following in vitro commissural section of the paired SCN showed a similar peak in spontaneous discharge activity during the projected light phase (between CT 06.00 an...

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