With the development of more compact and efficient ways of implementing digital logic on a silicon chip, most of the signal processing is being performed in the digital domain. The design of an efficient configurable digital decimation filter is focused in work. The Cascaded Integrator-Comb (CIC) filters are used as decimation filter. The five stage CIC filter is proposed in this paper. It does...

In this paper, a new design of the CIC (Cascaded-Integrator-Comb) FIR (Finite Impulse Response) filter functions is presented by spreading the delays in the comb stages. In order to validate theoretical design, a few test examples are designed for different filter parameters. The superiority of the new CIC filter functions is established by comparing these novel CIC FIR architectures with exist...

Dysregulation of the pathways that preserve mitochondrial integrity hallmarks many human diseases including diabetes, neurodegeration, aging and cancer. The mitochondrial citrate transporter gene, SLC25A1 or CIC, maps on chromosome 22q11.21, a region amplified in some tumors and deleted in developmental disorders known as velo-cardio-facial- and DiGeorge syndromes. We report here that in tumor ...

In this paper, we present a novel color independent components based SIFT descriptor (termed CIC-SIFT) for object/scene classification. We first learn an efficient color transformation matrix based on independent component analysis (ICA), which is adaptive to each category in a database. The ICA-based color transformation can enhance contrast between the objects and the background in an image. ...

To examine the role of circulating immune complexes (CIC) in infective endocarditis, we studied 64 patients with infective endocarditis for the presence of CIC by the polyethylene-glycol (PEG)-precipitation test and the Clq binding test. This study was repeated during the course of the disease in 23 patients. CIC were found in 84 per cent of patients (66 per cent with acute infective endocardit...

It has recently been reported that many immunological abnormalities including the presence of TSH-receptor antibody (TRAb) were found in Graves' disease (GD). Circulating immune complexes (CIC) have also been detected in the serum of patients with GD as observed in systemic lupus erythematosus, which is thought to be a typical model of immune complex disease. The role of CIC in pathogenesis of ...

Line Associated Bloodstream Infections And Nosocomial Bacteremia Mark Shelly, MD; Linda Greene, RN, MPS, CIC; Lynne Brown, RN, MBA, CIC; Sherry Romig, RN; Ann Marie Pettis, RN, BSN, CIC; Infectious Disease, University of Rochester Medical Center, Rocheseter, NY; Infectious Disease, Highland Hospital, Rochester, NY; Infection Prevention, Highland Hospital, Rochester, NY; Infection Prevention, Un...

BACKGROUND The therapeutic effect of inhaled corticosteroids (ICS) may be affected by the metabolism of the drug in the target organ. We investigated the in vitro metabolism of beclomethasone dipropionate (BDP), budesonide (BUD), ciclesonide (CIC), and fluticasone propionate (FP) in human lung precision-cut tissue slices. CIC, a new generation ICS, is hydrolyzed by esterases in the upper and lo...

A1 GCC2011 – 25 years of computational chemistry meetings Frank Oellien, Uli Fechner, Thomas Engel GDCh-CIC Division Chair, Intervet Innovation GmbH – MSD Animal Health, Zur Propstei, 55270 Schwabenheim, Germany; GDCh-CIC Division Board Member, Beilstein-Institut zur Förderung der Chemischen Wissenschaften, Trakehner Str. 7-9, 60487 Frankfurt, Germany; GDCh-CIC Division Co-Chair and Conference ...