the world hypertension day celebrates 17 th of may of every year by concentrating on an important global health subject. for world hypertension day (whd) 2014, they have chosen “know your blood pressure “as the theme. chronic kidney disease is a worldwide public health puzzle and hypertension is one the most important cause of damage to the kidneys. in fact by improved screening, diagnostic eff...

introduction: corticosteroids are routinely used in management of chronic obstructive pulmonary disease (copd) exacerbation. the main purpose of present study was to compare the efficacy of methyl prednisolone (mp) and dexamethasone (dxm) for this purpose. methods: adult copd patients entered the present clinical trial. all patients received standard treatment on admission and were then divided...

introduction and aims: microscopic colitis has been generally recognized as lymphocytic colitis and collagenous colitis: two inflammatory diseases of large intestine without a definite origin. the colon appears normal by colonoscopy. so, biopsy of the colonic mucosa is mandatory for diagnosis. materials and methods: as a descriptive design we assessed epidemiological, clinical and laboratory fi...

as the world’s population continues to age, practitioners encounter increasing numbers of older patients with end-stage renal disease (esrd) who require renal replacement therapy (rrt). conservative management may be considered in older patients and has been shown to offer comparable survival rates and hospital-free days to rrt patients. at present, for those who choose rrt, hemodialysis is the...

conclusions spironolactone combined with aceis or arbs leads to reduction of proteinuria in chronic kidney disease and therefore reduction of progression of the disease. objectives the study was designed to assess the effects of spironolactone as the aldosterone antagonist combined with acei or arb drugs to reduce proteinuria in chronic kidney disease to prevent its progression. patients and me...

background: hepatitis e virus is an enterically transmitted virus that is endemic in south asia and this virus is one of the most important cause of acute hepatitis in this region. although hepatitis e virus (hev) is not a leading cause for chronic hepatitis, the role of hev in exacerbation of chronic liver disease is certain. materials and methods: 100 cirrhotic cases (50 hepatitis b and 50 he...

in this study, we report a mutation in cybb gene in a patient with x-cgd (diagnosed on the base of family history, ndt test, dhr 123 assay). mutation in cybb gene was detected using sscp analysis (single-strand conformation polymorphism) followed by sequencing. during screening for mutations in the cybb gene we observed 880 c t in exon 8. this mutation resulted in 290 arg stop. we also observed...

objective(s):micrornas (mirnas) are small non-coding rna molecules that regulate gene expression. they have important roles in kidney development, homeostasis and disease, and participate in the onset and progression of tubulointerstitial sclerosis and end-stage glomerular lesions that occur in various forms of chronic kidney disease (ckd). in the present study, we elucidated the role of micror...

nonencapsulated, nontypeable hemophilus influenzae (nthi) remains an important cause of acute otitis and respiratory diseases in children and adults. nthi bacteria are one of the major causes of respiratory tract infections, including acute otitis media, cystic fibrosis, and community-acquired pneumonia among children, especially in developing countries. the bacteria can also cause chronic dise...

conclusions the fev1/fev6 ratio can be used as a valid surrogate for fev1/fvc in the diagnosis of airway obstruction, especially for screening purposes in high-risk populations for copd. moreover, fev6 is an acceptable alternative for fvc in detection of restrictive pattern. results this study shows that the current cut-off points used to detect obstruction and restriction can be replaced by fe...