Pain is an unpleasant sensory and emotional experience associated with actual or potential tissue damage and it is one of the major symptoms in arthritis. Pain is also the sensory modality that alerts patients so that it leads to protective responses. Pain also informs the patient that there is a potential noxious threat, which brings him or her to the doctor for diagnosis and treatment of his ...

background: chronic musculoskeletal pain is a worldwide health problem. anxiety and depression are common among patients suffering from chronic pain. self-management strategies are used to help patients manage the emotional distress associated with pain. aim: to evaluate the effects of cognitive pain self-management program (cpsmp) on depression, anxiety, and stress in women with chronic pain. ...

objective: the present study aimed to compare prospective and retrospective memory impairment and attention deficit in people suffering from chronic low back pain with those cognitive functions in healthy subjects. furthermore, this study examines the relation between severity and duration of pain and prospective and retrospective memory impairment and attention deficit. methods: the research w...

A failure in the control of proliferation of cerebellar granule neuron precursor cells (GCPs), located in the external granular layer (EGL) of the cerebellum, gives rise to medulloblastoma. To investigate the process of neoplastic transformation of GCPs, we generated a new medulloblastoma model by crossing Patched1 heterozygous mice, which develop medulloblastomas with low frequency, with mice ...

OBJECTIVES 1) To compare two measurement models of the BDI in chronic pain sufferers to see which provides the better fit; 2) to assess whether model fit differs for a facial pain sample compared to a sample of pain sufferers attending a multidisciplinary pain clinic; and 3) to establish which affective and somatic sub-scales of the BDI could be used in chronic pain research. DESIGN Two group...

BACKGROUND AND OBJECTIVE A single session of repetitive transcranial magnetic stimulation (rTMS) over motor cortex had been reported to produce short term relief of some types of chronic pain. The present study investigated whether five consecutive days of rTMS would lead to longer lasting pain relief in unilateral chronic intractable neuropathic pain. PATIENTS AND METHODS Forty eight patient...

BACKGROUND Non-steroidal anti-inflammatory drugs (NSAIDs) are used routinely to control pain and inflammation after surgery in dogs. Robenacoxib is a new NSAID with high selectivity for the cyclo-oxygenase (COX)-2 isoform of COX. The objective of this study was to evaluate the efficacy and tolerability of robenacoxib for the management of peri-operative pain and inflammation associated with sof...

Two separate studies were carried out to determine if three visual analogue scales for various feelings including pain could be marked consistently by patients, without reference to previously completed scales. Sixty patients undergoing extraction of their lower third molars had measurements of acute preoperative anxiety, expected postoperative pain and postoperative perceived pain three times ...

Objective. To assess reliability, validity, and responsiveness of a 29-item short-form version of the Patient Reported Outcomes Measurement Information System (PROMIS) and a novel “impact score” calculated from those measures. Design. Prospective cohort study. Setting. Rural primary care practices. Subjects. Adults aged 55 years with chronic musculoskeletal pain, not currently receiving prescri...