Introduction: Citelli’s abscess is an extratemporal complication of otitis media. It occurs when pus from the mastoid tip trickles down along the posterior belly of the digastric muscle to the occipital and cervical region. It is a very unusual presenting complication of chronic otitis media with no available data in the until now.   Case Report: A 10-year-old female was presented to our outpat...

the middle ear is the most prevalent disease of childhood. The other areas of the temporal bone which can be contiguous with the middle ear, including the mastoid, petrousus apex and perilabyrinthine air cells, may also be involved. Otitis media can be further divided into acute otitis media (AOM) without effusion, otitis media with effusion (OME), chronic suppurative otitis media (COM) with or...

We present a case of a 38-year-old man who had presented tinnitus, ear fullness, otalgia and otorrhea for 5 months, without improvement through the use of topical antibiotic drops. He had mixed hearing loss of moderate severity. He underwent mastoidectomy because of suspected chronic suppurative otitis media, but continued to present hearing loss, otorrhea and tympanic membrane perforation. In ...

BACKGROUND Previously rare A2ML1 variants were identified to confer otitis media susceptibility in an indigenous Filipino community and in otitis-prone US children. The goal of this study is to describe differences in the middle ear microbiome between carriers and non-carriers of an A2ML1 duplication variant that increases risk for chronic otitis media among indigenous Filipinos with poor healt...

Chronic suppurative otitis media (CSOM) is a chronic inflammation of the middle ear and mastoid cavity. Clinical features are recurrent otorrhoea through a tympanic perforation, with conductive hearing loss of varying severity. Experts dispute the duration of otorrhoea required to determine it as a chronic infection the World Health Organization's definitions suggest more than two weeks; others...

Cholesteatoma may be classified as either primary or secondary. Primary cholesteatoma occurs when its formation precedes the TM perforation and Secondary cholesteatoma develops from an ingrowth of skin through a TM perforation. Chronic Secretory Otitis Media (CSOM) In chronic secretory otitis media, fluid may be present for more than two months in the middle ear behind a TM with increased vascu...

High-mobility group box 1 (HMGB1) is a nuclear non-histone protein, playing a critical role as a mediator between innate and acquired immunity; when released extracellularly, it coordinates the cellular stress response (under necrosis, bacterial lipopolysaccharide stimulation) and acts as an inflammatory marker and cytokine. The aim of the study was to demonstrate whether HMGB1 is over-expresse...

Berling Holm, K. 2017. The Chorda Tympani Nerve. Role in Taste Impairment in Middle Ear Disease and after Ear Surgery. Digital Comprehensive Summaries of Uppsala Dissertations from the Faculty of Medicine 1306. 54 pp. Uppsala: Acta Universitatis Upsaliensis. ISBN 978-91-554-9837-5. The chorda tympani nerve, also known as the taste nerve, runs uncovered through the middle ear cavity, a localizat...

Chronic suppurative otitis media (CSOM) is a chronic inflammation of the middle ear and mastoid cavity. Clinical features are recurrent otorrhoea through a tympanic perforation, with conductive hearing loss of varying severity. Experts dispute the duration of otorrhoea required to determine it as a chronic infection the World Health Organization's definitions suggest more than two weeks; others...

Chronic otitis media, because of its many facets, continues to be an absorbing problem. Each case presents a fresh challenge and there is no routine treatment. A brief review of the changes in our thinking over the past 30 years may be instructive, always bearing in mind that latter-day developments have not been so consistently successful that we can afford to belittle the achievements of our ...