Background:Brucella spp. are facultative intracellular pathogens that can cause chronic infections in many tissues and organs. Objectives: To investigate serum dermcidin, salusin-alpha, salusin-beta and TNF-alpha levels and their correlation with each other in patients with acute brucellosis. Methods: From 50 patients hospitalized upon...

A basic feature of the host-parasite relationship in brucellosis is the intracellular localization of Brucella in the tissues of animals and man (1-6). This intracellular parasitism is a contributing factor in the tendency of the disease to become chronic. Experimental studies have shown that intracellular Brucella organisms are afforded protection against antibiotics, and also against the leth...

UNLABELLED Brucellosis is a worldwide zoonosis with a high degree of morbidity in humans. In Bosnia and Herzegovina a progressive increase of brucellosis among humans is evident. As the clinical picture of human brucellosis is fairly non-specific, a definitive diagnosis requires isolation of the causative organism, or the demonstration of the high levels of specific antibodies, or seroconversio...

Introduction: Brucellosis is still endemic in Turkey and presents a major public health risk. The aim of this study wasto investigate the clinical and laboratory properties and complications of brucellosis cases. Methodology: The files of 370 patients (162 males, 208 females) with brucellosis between March 2006 and January 2012 were analyzed retrospectively. Results: The mean age of patients wa...

Introduction: Brucellosis is a zoonotic infection caused by brucella species. It is an endemic disease in the Mediterranean region. It may affect different organ systems with osteoarticular involvement in the form of peripheral arthritis, sacroiliitis and spondylitis being the most common and serious complication of the disease and it may lead to severe and irreversible sequelae. The diagnosis ...

Background. Brucellosis is one of the most common diseases of humans and animals and its clinical manifestations differ from asymptomatic infection to chronic illness associated with recurrence of symptoms. This study aimed to evaluate the prevalence of brucellosis in asymptomatic children 7 to 12 years old in Kahak, Iran. Methods. In this study, 186 children 7 to 12 years old were evaluated. D...

TO THE EDITOR—Brucellosis is an infectious disease prevalent in many countries , with half a million new cases reported each year [1, 2]. Brucellosis can easily become chronic, resulting in great suffering and health burden for the patient due to treatment failure and relapse. Timely and accurate diagnosis is a prerequisite for efficient treatment and prevention of chronic infection [3]. Howeve...

background: brucellosis is the major bacterial zoonoses of global importance caused by brucella spps. fcγriia receptor plays a central role in phagocytosis of igg2-opsonized bacteria. fcγriia exhibits allelic polymorphisms with different capacities for binding igg2 and phagocytosis. cells expressing fc γ riia-h131, bind more efficiently to complexes of igg2 than those expressing the fc γ rii a ...