A cross-sectional study of a random sample of 976 coloureds (mixed race) of the Cape Peninsula, ages 15 to 64 years old, revealed a population with unexpectedly high levels of high density lipoprotein (HDL) cholesterol. The mean level for men was 55.4 +/- 16.1 mg/dl (SD) and for women, 60.8 +/- 16.0 mg/dl. The ratio of HDL cholesterol to total cholesterol expressed as a percentage was 26.3% +/-...

In a prospective epidemiologic study in company employees in Westfalia aimed at improving early diagnosis of coronary heart disease in 3069 men and 1387 women, concentrations of HDL-apolipoprotein A-I and HDL-cholesterol were measured and the results were correlated with several risk factors of coronary heart disease. A negative correlation between hypertriglyceridaemia and HDL-cholesterol (r =...

background: studies demonstrated controversial results on subclinical hypothyroidism (sch) regarding lipid profile alteration with or without levothyroxine treatment. the purpose of this study is to investigate the effects of levothyroxine on serum lipids in sch. materials and methods: one hundred patients with sch referred to taleghani hospital in kermanshah were recruited and randomly assigne...

in india, the occurrence of diabetes mellitus is on increase and needs to be addressed properly. herbal remedies are considered most suitable for the management of type 2 diabetes due to their traditional acceptability and availability, low costs, and fewer side effects. traditionally bauhinia tomentosa l. (family- fabaceae) is used in the treatment of diabetes in india. aqueous extract and alc...

Background Recently, the LDL/HDL-cholesterol ratio has become recognized as a stronger risk predictor of cardiovascular diseases than each lipid parameter. However, the association between LDL/HDL-cholesterol ratio and aortic atherosclerosis has not been elucidated yet. Using MRI, we investigated the associations between thoracic and abdominal aortic atherosclerosis and LDL/HDL-cholesterol rati...

Prospective population studies have shown that a raised concentration of high density lipoprotein (HDL) cholesterol is associated with a reduced incidence of coronary events and atherosclerotic progression. 2 According to one paradigm any raised concentration of HDL cholesterol is beneficial to health. This is, however, challenged by two unexplained observations. Firstly, in populations with he...

cardiovascular diseases with an incidence of approximately 50% are the main causes of death in most advanced countries and an increasing trend in the developing world as well. the world health organization estimates that 12 million people per year worldwide die from cardiovascular diseases. cardiovascular diseases are becoming an increasing problem worldwide and hypercholesterolemia has been co...

OBJECTIVE A recent observational study with almost 2 million men reported an association between low high-density lipoprotein (HDL) cholesterol and worse kidney function. The causality of this association would be strongly supported if genetic variants associated with HDL cholesterol were also associated with kidney function. APPROACH AND RESULTS We used 68 genetic variants (single-nucleotide...