We describe the first family report of ARC syndrome (arthrogryposis multiplex congenita, renal dysfunction, and cholestasis) diagnosed in Turkey. ARC syndrome is a rare cause of cholestatic jaundice and skeletal abnormalities in the neonatal period. Fanconi-like renal tubular dysfunction completed the clinical picture. Consanguinity and affected membership are the other typical components of th...

Liver and biliary tree scintigraphy and magnetic resonance cholangiography (MRC) have taken the place of the duodenal tube test (DTT) in the study of cholestatic jaundice due to extrahepatic biliary atresia (EBA). The usefulness of DTT associated with abdominal ultrasound (AUS) in the diagnosis of EBA was demonstrated in 4 patients presenting with cholestatic jaundice that underwent DTT and AUS...

Dear Editor, Outside of mid-western United States,1 histoplasmosis is endemic in pockets of Asia (like Indonesia) and Europe (Italy, Hungary, Romania, Britain).2 It is caused by H. capsulatum, a fungus found in barns, old houses or soil contaminated with bird droppings. Airborne spores infect those who inhale it. Disease manifestation is myriad, ranging from a sub-clinical infection to an organ...

Introduction Acquired toxoplasmosis may present as acute hepatitis (Vischer, Bernheim and Engelbrecht, 1967; Weitberg et al., 1979; Bars et al., 1978; Kouba, Jira and Zitova, 1971). Bars et al. (1978) in a survey of the literature reported 11 such cases. Weitberg et al. (1979) reported a case of granulomatous hepatitis due to Toxoplasma gondii and suggested that the severity of hepatitis may be...

D-penicillamine is not generally considered to cause hepatic damage. Cholestatic jaundice developed in a patient with rheumatoid arthritis 4 weeks after penicillamine was added to his regimen, and he died in acute renal failure. The probability that penicillamine caused the cholestasis is discussed.

PATIENT Female, 60 FINAL DIAGNOSIS: Cholangiocarcinoma Symptoms: Abdominal pain • abdominal discomfort MEDICATION - Clinical Procedure: - Specialty: Oncology. OBJECTIVE Unusual natural history/clinical course. BACKGROUND Cholangiocarcinoma remains to be a challenging case to diagnose and manage as it usually presents in advanced stage and survival rate remains dismal despite the medical b...