To screen the wound healing activity of different extracts of Allium cepa L. in excision, incision and dead space wound models in albino rats. The tubers of Allium cepa L. (Family Liliaceae) were exhaustively defatted with petroleum ether (40-60C) and the marc was subjected to continuous extraction with solvent ether, chloroform, alcohol and chloroform water I.P. All the extracts were tested fo...

This study rated antiviral activity of Scutellaria baicalensis Georgi (S. baicalensis) extracts against influenza A virus subtypes, for example, pandemic 2009 H1N1, seasonal H1N1 and H3N2. Ethyl acetate (EtOAc) and chloroform extracts inhibited in vitro neuraminidase (NA) enzymatic activity and viral replication more than methanol (MeOH) extract. EtOAc extract demonstrated NA inhibition IC50 va...

Xanthine oxidase is a key enzyme responsible for hyperuricemia, a pre-disposing factor for Gout and oxidative stress-related diseases. Only two clinically approved xanthine oxidase inhibitors Allopurinol and Febuxostat are currently used for treatment of hyperuricemia. However, owing to their side effects there is a need for new non-purine-based selective inhibitors of xanthine oxidase. In the ...

Petroleum ether, chloroform and methanol extracts of A. maciverae were studied in vitro and in vivo for activity against Trypanosoma brucei brucei in Swiss albino mice. Thereafter, the chloroform extract which showed the highest activity in both in vitro and in vivo assessments was subjected to bioassay-guided fractionation. The crude extracts and the fractions of the chloroform extract of A. m...

Ziziphus mauritiana L., is a fruit tree well known for its nutritional and medicinal benefits. The aim of the current study was to investigate the chemical composition as well as biological (antioxidant, antimicrobial, antitumor and anticancer) attributes of different solvent extracts from the leaves of Ziziphus mauritiana. It was established by colorimetric method that chloroform extract had g...

In vitro cytotoxic potential of extracts (95% and 50% ethanolic extract and hot water extract at concentration of 100 microg/ml) from leaves of Holarrhena antidysenterica was evaluated against fourteen human cancer cell lines--A-549, COLO-205, DU-145, HeLa, HEP-2, IMR-32, KB, MCF-7, NCI-H23, OVCAR-5, SiHa, SK-N-MC, SW-620 and ZR-75-1 from nine different tissues (breast, colon, cervix, CNS, lung...

The antibacterial activity of Citrus karna fruit peel extracts was evaluated on bacteria strains like Escherichia coli, Pseudomonas aeruginosa, Staphylococcus aureus and Bacillus subtilis. Hexane, chloroform and methanol were used for extraction and the antibacterial activity was performed by agar well diffusion method. The results were compared with ampicillin, a commercial antibacterial agent...

Tewtrakul, S., Subhadhirasakul, S., Kummee, S Anti-HIV-1 integrase activity of medicinal plants used as self medication by AIDS patients Songklanakarin J. Sci. Technol., 2006, 28(4) : 785-790 The extracts of selected medicinal plants used as self medication by AIDS patients were investigated for their inhibitory activities against HIV-1 integrase (HIV-1 IN) using the multiplate integration assa...

The objective of this research was to analyze the anti-diabetic properties of the bioactive compounds extracted from P. urinaria using molecular docking servers. Two extracts were prepared using distilled water and chloroform as solvents by optimized maceration procedure. Determination of phytochemical constituents of these extracts was then carried out by using standard set of protocols. GC-MS...

The results of our previous investigations on extracts of selected marine algae showed that Caulerpa peltata and Padina gymnospora had more promising antiproliferative and antioxidant activities than Gelidiella acerosa and Sargassum wightii. Based on these results, the more active chloroform extract of C. peltata and ethyl acetate extract of P. gymnospora were further analyzed for their constit...