Ion transport properties of grape root lipids were measured as liquid-membrane permeability. Phosphatidylcholine exchanged chloride very slowly against carbonate and bicarbonate but more rapidly against nitrate, phosphate, and sulfate. Exchange of chloride against nitrate was rather low for the phosphatidylcholine and phosphatidylethanolamine lipid fractions; monogalactose diglyceride was by fa...

This study investigates the mechanical and durability properties of 12 ultra-high performance fiber reinforced concrete (UHPFRC) mixes manufactured using alternate aggregate sources. Natural gabbro aggregates (GA), steel slag (SSA), recycled (RCA) were employed as coarse aggregates. The volume was limited to 12.5% total UHPC volume. Three types fibers employed: macro hooked-end fibers, micro st...

® The contents of this report reflect the views of the authors, who are responsible for the facts and the accuracy of the information presented herein. This document is disseminated under the sponsorship of the Department of Transportation University Transportation Centers Program, in the interest of information exchange. 16. Abstract This study focused on the use of nanotechnology in concrete ...

Mutations in the WNK4 gene cause pseudohypoaldosteronism type II (PHAII), an autosomal-dominant disorder of hyperkalemia and hypertension. The target molecules of this putative kinase and the molecular mechanisms by which the mutations cause the phenotypes are currently unknown. Although recent reports found that expression of WNK4 in Xenopus oocytes causes inhibition of the thiazide-sensitive ...

Aquaporins (AQPs) have a broad range of cellular and organ functions; however, nontoxic inhibitors of AQP water transport are not available. Here, we applied chromophore-assisted light inactivation (CALI) to inhibit the water permeability of AQP1, and of two AQP4 isoforms (M1 and M23), one of which (M23) forms aggregates at the cell plasma membrane. Chimeras containing Killer Red (KR) and AQPs ...

There are two major transport pathways across epithelia: a transcellular pathway through cells and a paracellular pathway between cells. Previous electrophysiological studies in mosquito Malpighian tubules suggested that the neuropeptide leucokinin-VIII (LK-VIII) increases the chloride permeability of the paracellular pathway. To test the effect of LK-VIII on the paracellular pathway further, w...

This case study aimed to compare the differences in durability and prestress loss between normal-weight-concrete (NC) lightweight-aggregate-concrete (LWC) prestressed box girders, which were constructed at same time area, so as verify superiority of using synthetic lightweight aggregate (LWA) made from reservoir sediments bridges. For NCs LWCs used basic mechanical properties (compressive stren...

OBJECTIVE To develop a simple, physiologically based mathematical model of pancreatic duct cell secretion using experimentally derived parameters that generates pancreatic fluid bicarbonate concentrations of >140 mM after CFTR activation. METHODS A new mathematical model was developed simulating a duct cell within a proximal pancreatic duct and included a sodium-2-bicarbonate cotransporter (N...