The retention and adhesion of melamine formaldehyde (MF) microcapsules on a model fabric surface in aqueous solution were investigated using a customised flow chamber technique and atomic force microscopy (AFM). A cellulose film was employed as a model fabric surface. Modification of the cellulose with chitosan was found to increase the retention and adhesion of microcapsules on the model fabri...

Composite chitosan-magnetite microparticles (Fe-Cc) were evaluated as a new adsorbent for cobalt and nickel ion separation from aqueous solutions. Sorption batch experiments were conducted for optimizing the pH, initial target ion concentration and adsorbent amount. The experimental data were fitted using Langmuir, Freundlich, and respectively DubininRadushkevich isotherm models. The Langmuir m...

Chitosan has been the subject of interest for its use as a polymeric drug carrier material in dosage form design due to its appealing properties such as biocompatibility, biodegradability, low toxicity and relatively low production cost from abundant natural sources. However, one drawback of using this natural polysaccharide in modified release dosage forms for oral administration is its fast d...

Chitosan coated alginate microcapsules were developed as oral sustained delivery carriers for anti tubercular drugs in order to improve patient compliance, to reduce dose/dosing frequency in the management of tuberculosis (TB), which otherwise demands prolonged chemotherapy. Alginate–chitosan microparticles encapsulating three frontline anti-tuberculosis drugs (ATDs), rifampicin, isoniazide and...

Regulation of gene expression using small interfering RNA (siRNA) is a promising strategy for research and treatment of numerous diseases. However, siRNA cannot easily cross the cell membrane due to its inherent instability, large molecular weight and anionic nature. For this reason, a carrier that protects, delivers and unloads siRNA is required for successful gene silencing. The goal of this ...

Spherical microparticles, capable of responding to magnetic fields, were prepared by encapsulating dextran-coated Fe3O4 nanoparticles into chitosan poly(acrylic acid) (PAA) microspheres template. The obtained magnetic microspheres were characterized by transmission electron microscopy (TEM), Fourier transform infrared spectroscopy (FT-IR), scanning electron microscopy (SEM), X-ray powder diffra...