In relational database systems, the join is one of the most expensive but fundamental query operations. Among various join methods, the hash-based join algorithms show great potential as they lend themselves for parallelization. Although performance of the hash join algorithm has been evaluated for many architectures, to the best of our knowledge, it has not been evaluated for the COMA memory a...

There has been a convergence in computer architecture toward a distributed memory implementation of a shared memory user model. This has brought about the possibility of using a very large number of processors, on NWP applications, from the realm of research into reality. The simplicity of the shared memory model has meant that porting the very large Unified Model can be approached. However, al...

To stay competitive, organizations frequently need to access and manage knowledge resources external to their boundaries. Inter-organizational relationships (IORs) are a typical mechanism to achieve these goals. Relational governance mechanisms are germane to this context and knowledge sharing routines (KSR), a component of relational governance, are critical to knowledge management in such sit...

groundwaters hydrochemistry of ayrakan and cheshmeh shotori areas and geochemistry of rare earth elements, indicate ayrakan alkali granite as the origin of uranium and other dissolved elements in groundwaters of these areas. geochemical and hydrogeochemical studies as well as the trend of uranium and thorium transition and mobility in aqueous environments of these areas indicate uranium adsorpt...

MEK1 and MEK2 are related protein kinases that participate in the RAS-RAF-MEK-ERK signal transduction cascade. This cascade participates in the regulation of a large variety of processes including apoptosis, cell cycle progression, cell migration, differentiation, metabolism, and proliferation. Moreover, oncogenic mutations in RAS or B-RAF are responsible for a large proportion of human cancers...

Many cancers, including those of the colon, lung, and pancreas, depend upon the signaling pathways induced by mutated and constitutively active Ras. The molecular scaffolds Kinase Suppressor of Ras 1 and 2 (KSR1 and KSR2) play potent roles in promoting Ras-mediated signaling through the Raf/MEK/ERK kinase cascade. Here we summarize the canonical role of KSR in cells, including its central role ...

The eyes are subdivided from the rostral diencephalon in early development. How the neuroectoderm regulates this subdivision, however, is largely unknown. Taking advantage of embryonic stem cell (ESC) culture using a Rax reporter line to monitor rostral diencephalon formation, we found that ESC-derived tissues at day 7 grown in Glasgow Minimum Expression Media (GMEM) containing knockout serum r...