Mixing aqueous solutions of sodium diclofenac (DIC-Na) and ranitidine hydrochloride (RAN·HCl) afforded an off-white solid (DIC-RAN) that was investigated from the microscopic, thermal, diffractometric, spectroscopic, and functional (chemometrics-assisted dissolution) points of view. The solid has a 2:1 (DIC:RAN) molar ratio according to (1)H nuclear magnetic resonance spectroscopy. It is therma...

This study investigated the organic and inorganic constituents of healthy leaves and Candidatus Liberibacter asiaticus (CLas)-inoculated leaves of citrus plants. The bacteria CLas are one of the causal agents of citrus greening (or Huanglongbing) and its effect on citrus leaves was investigated using laser-induced breakdown spectroscopy (LIBS) combined with chemometrics. The information obtaine...

chemometric techniques in spectral analysis have gained importance in the quality control of  the drugs mixtures and pharmaceutical formulations containing two or more drugs with overlapping spectra. since theophylline and etophylline have common chromophore, they cannot be analyzed simultaneously using conventional uv methods. simultaneous spectrophotometric determination of etophylline and th...

NMR and chemometrics was applied to understand the variations in chemical composition of coconut water under different processing. Six processing treatments were applied to coconut water and analyzed: two control (with and without sulphite), and four samples thermally processed at 110°C and 136°C (with and without sulphite). Samples processed at lower temperature and without sulphite presented ...

[1]. Microarray. Gene Expression Data Analysis. Causton, H. C.; Quackenbush, J.; Brazma, A. (2003), (Blackwell, Oxford, UK) [2]. Ross, D T et al.. Systematic variation in gene expression patterns in human cancer cell lines. Nature Genetics (2000), 24(3), 227-235. [3]. Crescenzi, M; Giuliani, A. The main biological determinants of tumor line taxonomy elucidated by a principal component analysis ...

The monomer-dimer equilibrium and thermodynamic of several ionic dyes (Neutral Red, Nile Blue A, Safranine T and Thionine) has been investigated by means of spectrophotometric and chemometrics methods. The dimerization constants of these ionic dyes have been determined by studying the dependence of their absorption spectra on the temperature in the range 20-75 degrees C at concentrations of Neu...

*Correspo Danish In Denmark, E-mail: sf Contract/ Fisheries. Outliers may hamper proper classical multivariate analysis, and lead to incorrect conclusions. To remedy the problem of outliers, robust methods are developed in statistics and chemometrics. Robust methods reduce or remove the effect of outlying data points and allow the ‘good’ data to primarily determine the result. This article revi...

Abstract: Aim: Multivariate methods, particularly Classical Least Square, Inverse Square (ILS), Partial and Principal Component Regression are invented for the quantitation of Abacavir sulphate (ABA), Lamivudine (LAM) Dolutegravir sodium (DOL) in their combined tablet formulation. Materials Methods: Chemometrics is integration statistical mathematical approaches to analytical data order extract...