Background: About 40 thousand newborns are delivered annually with fetal alcohol syndrome (FAS). It induces serious CNS complications. Methods: In a review of, the word “fetal alcohol syndrome” was searched in PubMed and Google Scholar and the retrieved articles were summarized. Results: Many studies showed that alcohol can cause more defects in fetus than heroin, cocaine and marijuana. The pos...

The harmful use of alcohol inflicts great deal of social and economic losses on individuals and societies. Given the increase in world population and the predicted increase in alcohol consumption, the alcohol related burden of disease progressively catches higher ranks in the list of factors threatening humans' life. It has been considered that the social and economic burden related to alcohol ...

Alcohol, with its impact on both communicable and non-communicable diseases, is considered as the third global public health priority. Alcohol ranked third among causes of ill health and premature death, and ranked second in terms of cost among all the substances of abuse, after tobacco, even though nearly half the world’s population drinks alcohol. In most countries, where alcohol is considere...

Five clonal cell strains of an early-passage normal rat liver epithelial cell line were transformed spontaneously using the protocol of "selective culture" condition. Twelve cell lines were established from the tumors produced after injecting these transformed cells into 1-day-old syngeneic rats. The phenotypic expressions of these spontaneously transformed tumor cell lines were studied and com...

Background: During imposed war (1980-1988) Iraq frequently used chemical warfare particularly mustard gas. Skin is frequently involved in victims. Objective: Our main objective was to evaluate chronic skin manifestations due to exposure to mustard gas 10-19 years after exposure in a case-control study. Patients and Methods: 101 chemically wounded combators and 121 non-chemically wounded c...

Chemically induced rat liver nodules and cancers characteristically demonstrate a limited capacity to activate xenobiotics to reactive species mainly because of decreased amounts of cytochrome P-450. These lesions also show enhancement of xenobiotic detoxication by such mechanisms as enzymic conjugation or reduction of cytotoxic species. We recently demonstrated a similar pattern of metabolic a...