In the course of the routine use of NMR as an aid for organic chemistry, a day-to-day problem is the identification of signals deriving from common contaminants (water, solvents, stabilizers, oils) in less-than-analytically-pure samples. This data may be available in the literature, but the time involved in searching for it may be considerable. Another issue is the concentration dependence of c...

We have developed an all-electronic digital microfluidic device for microscale chemical synthesis in organic solvents, operated by electrowetting-on-dielectric (EWOD). As an example of the principles, we demonstrate the multistep synthesis of [(18)F]FDG, the most common radiotracer for positron emission tomography (PET), with high and reliable radio-fluorination efficiency of [(18)F]FTAG (88 ± ...

Solvents represent an important group of environmental pollutants to which people are exposed daily in the workplace. The physico chemical properties of solvents may result in disturbances to cellular structures, including damage to DNA. However, the effects of mixtures of solvents are not well known. Mutations caused by environmental agents are related to cancer development and other degenerat...

Mono and bis hexamethylenetetramine iron(III) chloride, Fe(N C ,H ) CI (I) and Fe(N C ,H ) Cl (II) were synthesized by the reaction of iron(III) chloride and hexamethylenetetramine (HMTA) in chloroform. Chemical analysis and spectral results show the coordination of HMTA to the iron(III). Electronic transition spectra of compound I and I1 were also studied in coordinating and noncoordinatin...

Fmoc-amino acids were obtained from GL Biochem (Shanghai, China). All the other Starting materials were obtained from Alfa. Chemical reagents and solvents were used as received from commercial sources.

Aldehydes, ketones and imines were readily reduced by sodium borohydride, with the participation of a small amount of water, in good to excellent yields using PEG400 as catalyst in the absence of organic solvents.  2005 Society of Chemical Industry

Hydrofluoroethers are shown to be benign solvents to a wide variety of organic electronic materials, even at extreme conditions such as boiling temperature. Coupled with fluorous functional photoresist-acidsensitive semi-perfluoroalkyl resorcinarene, they open new frontiers for photolithographical patterning for organic electronic systems. Summary of Research: Organic electronics is emerging as...

Most processes used in the pharmaceutical industry are, by necessity, carried out in organic solvents. In many cases these solvents are volatile and sufficiently water-soluble to contaminate air emission and aqueous discharge streams, adding to the environmental burden and the cost of downstream processing and recovery operations. One example is the use of tetrahydrofuran (THF) as the solvent f...