1 Departamento de Microbiologı́a I, Inmunologı́a, Facultad de Medicina, Universidad Complutense, 28040 Madrid, Spain 2 Inmunotek SL, Alcalá de Henares, 28805 Madrid, Spain 3 School of Life and Health Sciences, Aston University, Birmingham B4 7ET, UK 4ATR, LLC, Worcester, MA 01606, USA 5Department of Mycobacteriology, National Institute of Infectious Diseases, Higashi-Murayama, Tokyo 189-0002, Japan

Graduate School of Integrated Arts and Sciences, Hiroshima University, Higashi-Hiroshima, Hiroshima 739-8521 Frontier Research System, The Institute of Physical and Chemical Research (RIKEN), Wako, Saitama 351-0198 AdSM, Hiroshima University, Higashi-Hiroshima, Hiroshima 739-8530 Center for Theoretical Physics, Physics Department, CSCS, The University of Michigan, Ann Arbor, MI 48109-1040, U.S....

Chediak-Higashi syndrome (CHS) is a very rare autosomal recessive immunodeficiency disorder characterized by partial albinism, recurrent pyogenic infections, and large granules in all granule-containing cells. The author describes a Thai girl who was the first case of CHS in Thailand. She presented in the accelerated phase of CHS, which leads to repeated infections and bleeding, often resulting...

Chediak-Higashi Syndrome is a pathology caused by mutation in the LYST gene, characterized immunodeficiency, oculocutaneous albinism, and neurological dysfunction resulting from neutrophil changes. Homozygotes die first decade of life. The study about literature review different sources, with articles extracted SciELO, LILACS, MEDLINE, Google Scholar, PubMed databases, published between 2000 20...