∗ Corresponding author. E-mail addresses: [email protected] (G. Migliorati), [email protected] (F. Nobile). http://dx.doi.org/10.1016/j.jco.2015.02.001 0885-064X/© 2015 Published by Elsevier Inc. 518 G. Migliorati, F. Nobile / Journal of Complexity 31 (2015) 517–542

Correspondence to Dr Wolfgang Wagner; [email protected] Visiting Ravenna, this ancient town near the Adriatic Sea in Italy, cannot be called anything but a feast in culture. From AD 402 to AD 476, it was the capital of the Western Roman Empire. The city and its harbour later became the Italian stronghold of the Eastern Roman Empire (Constantinople/Istanbul). No wonder that busloads of tour...

Whether contemporary human populations are still evolving as a result of natural selection has been hotly debated. For natural selection to cause evolutionary change in a trait, variation in the trait must be correlated with fitness and be genetically heritable and there must be no genetic constraints to evolution. These conditions have rarely been tested in human populations. In this study, da...

BACKGROUND Little is known about the interaction between socio-economic status and 'protected characteristics' in Scotland. This study aimed to examine whether differences in mortality were moderated by interactions with social class or deprivation. The practical value was to pinpoint population groups for priority action on health inequality reduction and health improvement rather than a sole ...

To the Editor: We read with great interest the article by Abdoler et al. (1) on the ethics-based interpretation of phase 0 trials in cancer patients. In our opinion, drugs that consistently show favorable toxicity profile and beneficial therapeutic activity in preclinical models should be tested in anima nobile . This is particularly important for molecular targeted therapies, in which impressi...

Dendrobium nobile is one of the fundamental herbs in traditional Chinese medicine. Sesquiterpene alkaloids are the main active components in this plant. Due to weak ultraviolet absorption and low content in D. nobile, these sesquiterpene alkaloids have not been extensively studied using chromatographic methods. Herein, tandem mass spectrometry combined with liquid chromatography separation prov...