The semiconservative replication of telomeres is facilitated by the shelterin component TRF1. Without TRF1, replication forks stall in the telomeric repeats, leading to ATR kinase signaling upon S-phase progression, fragile metaphase telomeres that resemble the common fragile sites (CFSs), and the association of sister telomeres. In contrast, TRF1 does not contribute significantly to the end pr...

Local anaesthesia is the most common medium for pain control in most dental treatments. Physical appearance of syringe itself can be considered as a provoking factor for the emergence of dental fear and anxiety (DFA). In this research the patient reactions to local anaesthesia application devices, as one of the main causes for DFA emergence, were inquired. The sample comprised of 120 patients, ...

Financial investors often face an urgent need to predict the future. Accurate forecasting may allow investors to be aware of changes in financial markets in the future, so that they can reduce the risk of investment. In this paper, we present an intelligent computing paradigm, called the Complex Neuro-Fuzzy System (CNFS), applied to the problem of financial time series forecasting. The CNFS is ...

Objective: This study aimed to determine the prevalence of dental fear and its related factors among patients managed in a pediatric clinic university hospital Tanzania.
 Material Methods: was cross-sectional carried out at paediatric Muhimbili University Health Allied Sciences(MUHAS) between November 2018 April 2019. It included all aged 6 12 years. A questionnaire used this captured info...

BACKGROUND In dental examining rooms, children experience diagnostic and therapeutic pain related to dental procedures that may be associated with anxiety. Therefore, the main objective of the present study was to evaluate anxiety and pain levels related to dental procedures in children. METHODS Children in a Mexican pediatric dental clinic rated their dental anxiety using the Modified Dental...

[email protected] Gut microbiota play an important roles in induction of various cellular responses, including cytokine production. In this work, we examined the involvement of four intestinal strains in induction of the cytokine response (the relative expression of TNF-α, IL-6, and IL-8) in intestinal epithelial cells. Caco-2 cells were treated with cell-free supernatants (CFS) of four intestin...

Fungal deterioration is a barrier to the wide acceptance of fermented cereal foods from Africa. The use protective cultures natural approach controlling fungi in that also complies with clean label strategy. This study aims select antifungal lactic acid bacteria (LAB) previously isolated kunu-zaki bio-control this cereal-based Nigerian beverage. Strains Leuconostoc citreum (1), Limosilactobacil...

Recent studies have shown that the microbiota during early years of an individual’s life is affected by mode release childbirth, differing between caesarean section and newborns born vaginally. Here we reported selection nomadic lactobacilli for development a multi-strain probiotic gel to promote lactobacilli-dominated vaginal in pregnant women establish proper eubiosis new-born. Lactobacilli, ...

Background: Child dental fear is one of the behavior problems that dentists face in practice and has been linked to poor dental health. The main objectives of this study were to compare child and parental ratings of child dental fear and to assess the effect of child and parent characteristics on the ratings. Methods: The full version and the 6-item short version of the Children’s Fear Survey S...

We report the calculated visible spectrum of [FeIII(PyPepS)2]- in aqueous solution. From all-classical molecular dynamics simulations on the solute and 200 water molecules with a polarizable force field, 25 solute/solvent configurations were chosen at random from a 50 ps production run and subjected the systems to calculations using time-dependent density functional theory (TD-DFT) for the solu...