PURPOSE Although the cornea expresses high levels of clusterin (CLU), the role of CLU in the cornea is poorly understood. This study was performed to investigate the possible role of CLU in corneal epithelial homeostasis. METHODS CLU was overexpressed in 3T3 cells by transfection of a vector encoding full-length CLU (Clu-3T3). Colony-forming efficacy (CFE) was compared in mouse corneal cell l...

Although the existence of the limbal stem cell (LSC) niche is accepted, precise knowledge of its three-dimensional (3D) architecture remains incomplete. The LSC niche was explored on freshly excised and organ-cultured corneoscleral rims from human donors (n = 47), pigs (n = 15) and mice (n = 27) with full-field optical coherence microscopy (FFOCM). Limbal crypt features were detected in 90% of ...

Background: The beneficial effect of breastfeeding for the health of mothers and infants are well recognized. Breast milk is a novel source of the stem cells forming during pregnancy and lactation. In the present study, the colony forming efficiency (CFE) of breast milk-derived stem/progenitor cells in the breast milk of mothers with preterm delivery (gestational age o...

The plants of genus Corchorus have a folkloric repute to possess anti-inflammatory activity. The crude ethanolic extract of Corchorus fascicularis Lam. (CFE) was screened for presence of anti-inflammatory, free radical scavenging and calcium channel blocking (CCB) activities to validate its vernacular use. The 1,1-diphenyl-2-picrylhydrazyl (DPPH) assay was used to assess free radical scavenging...

This paper argues that a tunneling prefactor should appear in expressions for the tunneling probability D relevant to cold field electron emission CFE and in Fowler–Nordheim FN type equations. Except in the case of the “ideally smooth” parabolic barrier, a prefactor is always present for barriers where D can be found by exact solution of the Schrödinger equation. A review of the Jeffreys–Wentze...

Characterization of acoustic emission (AE) signals in loaded materials can reveal structural damage and consequently provide early warnings about product failures. Therefore, extraction the most informative features from AE is an important part characterization process. This study considers obtained bending experiments for carbon fiber epoxy (CFE) glass (GFE) composites. The research focused on...

BACKGROUND Drug-resistant epilepsy (DRE) is usually related to focal epilepsy (FE) and is present in up to 30% of patients. Several studies have found high rates of depressive symptoms and poor health related quality of life (HRQOL) in DRE patients but little information is available on these aspects for Spain. OBJECTIVE To determine the prevalence of depressive symptoms in a cohort of Spanis...

Porovnanie metód pre diskrétnu aproximáciu operátorov neceločíselného rádu In this paper we will present some alternative types of discretization methods (discrete approximation) for the fractional-order (FO) differentiator and their application to the FO dynamical system described by the FO differential equation (FDE). With analytical solution and numerical solution by power series expansion (...