نتایج جستجو برای: cf strategies

تعداد نتایج: 417044  

2008

Despite their ambiguous historical record, conservation/development interventions the world over have remained a popular environmental governance tool. One of the latest global ‘trends’ are interventions to establish so-called ‘Transfrontier Conservation Areas’ (TFCAs): large contiguous spaces that are principally aimed at conserving biological diversity across national boundaries. In line with...

2012
Götz Fabry Marianne Giesler

BACKGROUND Adequate use of different learning strategies is one of the most important prerequisites of academic success. The actual use of learning strategies is the result of an interaction between individual and situational variables. Against this background we conducted a longitudinal study with first year medical students to investigate whether individuals show different patterns in their u...

2015
Stephanie Ruffing F. -Sophie Wach Frank M. Spinath Roland Brünken Julia Karbach

Recent research has revealed that learning behavior is associated with academic achievement at the college level, but the impact of specific learning strategies on academic success as well as gender differences therein are still not clear. Therefore, the aim of this study was to investigate gender differences in the incremental contribution of learning strategies over general cognitive ability ...

پایان نامه :وزارت علوم، تحقیقات و فناوری - دانشگاه فردوسی مشهد - دانشکده علوم 1392

خانواده gnaphosidae یکی از بزرگترین خانواده های راسته aranea و دارای پراکنش جهانی می باشد. تا کنون، 14 جنس و 18 گونه از این خانواده از ایران گزارش شده است که تنها دو گونه آن از استان خراسان می باشد و این امر نشان دهنده اهمیت مطالعه این خانواده در این استان می باشد. سرخس به عنوان یکی از شهرستان های استان خراسان که در شمال شرقی ایران قرار گرفته و دارای مرز مشترک زیادی با کشور ترکمنستان می باشد به...

Journal: :Thorax 2011
Nicolas Regamey Peter K Jeffery Eric W F W Alton Andrew Bush Jane C Davies

Pulmonary disease is the most important cause of morbidity and mortality in cystic fibrosis (CF). Most patients with CF die from respiratory failure with extensive airway destruction. Airway remodelling, defined as structural airway wall changes, begins early in life in CF but the sequence of remodelling events in the disease process is poorly understood. Airway remodelling in CF has traditiona...

Journal: :Revista de investigacion clinica; organo del Hospital de Enfermedades de la Nutricion 2010
Margarita Chávez-Saldaña Emiy Yokoyama José Luis Lezana Alessandra Carnevale Miguel Macías Rosa M Vigueras Marisol López Lorena Orozco

INTRODUCTION Cystic fibrosis, the most common autosomal recessive disorder, is caused by defects in the CF transmembrane conductance regulator gene (CFTR) that encodes a chloride channel. To date, over 1,800 mutations have been described related to the causative gene of CF, showing a variable frequency among populations. In a previous extensive analysis of the CFTR locus in 97 Mexican patients,...

2012
Eugene H Chang Alejandro A Pezzulo David K Meyerholz Andrea E Potash Tanner J Wallen Leah R Reznikov Jessica C Sieren Philip H Karp Sarah Ernst Thomas O Moninger Nicholas D Gansemer Paul B McCray David A Stoltz Michael J Welsh Joseph Zabner

OBJECTIVES/HYPOTHESIS Chronic sinusitis is nearly universal in humans with cystic fibrosis (CF) and is accompanied by sinus hypoplasia (small sinuses). However, whether impaired sinus development is a primary feature of loss of the cystic fibrosis transmembrane conductance regulator (CFTR) or a secondary consequence of chronic infection remains unknown. Our objective was to study the early path...

2013
William T. Harris David R. Kelly Yong Zhou Dezhi Wang Mark Macewen James S. Hagood J. P. Clancy Namasivayam Ambalavanan Eric J. Sorscher

RATIONALE TGF-β, a mediator of pulmonary fibrosis, is a genetic modifier of CF respiratory deterioration. The mechanistic relationship between TGF-β signaling and CF lung disease has not been determined. OBJECTIVE To investigate myofibroblast differentiation in CF lung tissue as a novel pathway by which TGF-β signaling may contribute to pulmonary decline, airway remodeling and tissue fibrosis...

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