BACKGROUND Mixed medullary-follicular thyroid carcinoma denotes a rare and heterogeneous group of tumors displaying morphological and immunophenotypical features of both origins within the same lesion. METHOD We report a case of a 41-year-old woman with a lump in the right side of the neck, increasing in pain and size over several weeks. Serum levels of calcitonine (1140 ng/L) and carcinoembr...

BACKGROUND Parathyroid carcinoma is a rare malignancy, with an incidence of 0.5 to 4% of all cases of primary hyperparathyroidism. Surgery is the only curative treatment. CASE PRESENTATION We report the case of a 66-year-old man referred for a large suspicious substernal goitre associated with severe hypercalcemia due to hyperparathyroidism. After normalization of serum calcium levels, patien...

endocrine tumors of the pancreas (islet-cell tumors) are rare with neuroendocrine origin. the patient was a 41- year- old man, admitted with chief complains of epigastric mass feeling, dull abdominal pain, lack of appetite and weight loss up to 2-3 kg since 6 months ago. in physical examination, a mass was detected in epigaster and left upper quadrant (luq). in abdominal x-ray, a calcified mass...

background: solitary fibrous tumor (sft) is a mesenchymal tumor which is most commonly seen in the pleura; however it can be seen in other organs such as the meninge, gastrointestinal tract, soft tissue, bone, and skin. sft should be differentiated from other mesenchymal tumors in these organs. immunohistochemistry plays a pivotal role for the histopathologic diagnosis of this tumor. currently,...

background: very few studies have utilized specific criteria to assess mental disorders in brain tumor patients. this study aimed to diagnose mental disorders in this population using dsm-iv (depression, sleep, and mood) criteria. methods: from march 2007 to july 2009, the surgically treated patients with intracranial neoplasm were included in the study. these patients were examined in an ambul...

the most frequently mutated tumor suppressor gene found in human cancer is p53. in a normal situation, p53 is activated upon the induction of dna damage to either arrest the cell cycle or else induce apoptosis. however, when mutated, p53 is no longer able to properly accomplish these functions. our aim was to investigate p53 protein alteration in cases of basal cell carcinoma (bcc) and compare ...

0

primary malignant neoplasms of the pericardium are rare and are predominantly mesotheliomas, followed by benign localized fibrous mesothelioma, malignant fibrosarcoma, angiosarcoma and benign and malignant teratomas. 1 this article concerns an atypical presentation of this malignant tumor with symptoms and signs of pericardial effusion. this unusual feature was complete encasement of the heart ...

Objective: The use of a T-tube to manage complex laryngotracheal lesions, such as tracheal stenosis, tracheomalacia and tracheal injury, has previously been reported by other surgeons in the past. However, further validation of clinical details, including operative management and postoperative care, is needed. Methods: From January 1991 to May 2000, 53 patients, including 24 with post-tracheost...