nigella sativa (ns) (ranunculaceae family) is generally utilized as a therapeutic plant all over the world. the seeds of the plant have a long history of use in different frameworks of medicines and food. in islamic literature, it is considered as one of the greatest forms of therapeutics. it has been widely used to treat nervous system diseases such as memory impairment, epilepsy, neurotoxicit...

In this investigation the effects of excess vitamin A administration during the early embryonic period were studied. Intramuscular injection of a single dose of 15000,20000 or 25000 IU/kg vitamin A to pregnant Balb/c strain mice on either day 7,8,9 or 10 of gestation (vaginal plug= day 0 of gestation) produced major malformations in the central nervous system (CNS) including exencephaly, h...

Recently a new class of "designer drugs" has emerged on the drugs abuse market, known as "legal highs". Such drugs are legal to use and possess, and legal to supply. Mephedrone, a central nervous system stimulant, is the most widely experienced "legal high". This review presents any available information about psychoactive properties, safety profile, clinical data, and legislation of the new "l...

We report two infants with near miss sudden infant death syndrome events exhibiting seizure disorders after caffeine treatment, suggesting there is an infant subgroup diagnosed as near miss sudden infant death syndrome who have apnoea possibly with seizures whose seizure threshold may be lowered by central nervous system stimulants like caffeine.

in this investigation the effects of excess vitamin a administration during the early embryonic period were studied. intramuscular injection of a single dose of 15000,20000 or 25000 iu/kg vitamin a to pregnant balb/c strain mice on either day 7,8,9 or 10 of gestation (vaginal plug= day 0 of gestation) produced major malformations in the central nervous system (cns) including exencephaly, hydroc...

the close relationship between the immune system and the central nervous system (cns) has been well-studied. the cns regulates almost all the functions of the immune system; however, the effect and/or the control of the immune system on the cns has not been well-studied yet. recent reports suggest that the cns has its own defence mechanism(s). in this review, attempts have been made to discuss ...

post-traumatic stress disorder (ptsd) is an anxiety disorder that can typically occur after traumatic events in which the individual felt sever helplessness or horror. ptsd has a lifetime prevalence of 5–8% and women show higher prevalence than in compared with men. neuroinflammation is associated to anxiety and related disorders such as ptsd. it is an early, specialized immune reaction fallowi...