Research indicates long-duration, low-level noise exposures can induce plasticity in the auditory cortex, which can impair auditory perception; however, it is unclear if these functional changes originate more peripherally in the auditory pathway. Using a systems approach, we investigated the physiological plasticity that occurs in the cochlea and auditory midbrain following long-term, low-leve...

Auditory brainstem responses (ABRs) were evaluated during the postnatal development (P10-P180) of taiep rats, neurological mutants characterized by early abnormal myelin development and subsequent demyelination of the CNS. The disorder is produced by an autosomal recessive mutation trait that affects the oligodendrocytes but not the Schwann cells. After onset of ABRs (P12-P14), taiep rats and t...

Studies in the vertebrates have shown that the time-locking ability of central auditory neurons decreases progressively along the ascending auditory pathway. This decrease is presumably attributed to a progressive reduction in the fidelity of synaptic transmission and an increase in the influence of synaptic inhibition along the cascade. The extent to which neurons' intrinsic biophysical proper...

Mice are of paramount importance in biomedical research and their vocalizations are a subject of interest for researchers across a wide range of health-related disciplines due to their increasingly important value as a phenotyping tool in models of neural, speech and language disorders. However, the mechanisms underlying the auditory processing of vocalizations in mice are not well understood. ...

OBJECTIVE This study examined the plasticity of the central auditory pathway and accompanying cognitive changes in children with learning problems. METHODS Children diagnosed with a learning disability and/or attention deficit disorder worked with commercial auditory processing training software for 8 weeks; control groups consisted of normal-learning and learning-impaired children who did no...

Background: auditory evoked potentials (AEP) assess the neuroelectric activity on the auditory pathway from the auditory nerve to the cerebral cortex in response to an acoustic stimulus or event. Studies have demonstrated electrophysiological abnormalities in individuals with HIV/AIDS. Aim: to characterize the hearing electrophysiological manifestations in adults with HIV/AIDS by comparing the ...

Barn owls can localize a sound source using either the map of auditory space contained in the optic tectum or the auditory forebrain. The auditory thalamus, nucleus ovoidalis (N.Ov), is situated between these two auditory areas, and its inactivation precludes the use of the auditory forebrain for sound localization. We examined the sources of inputs to the N.Ov as well as their patterns of term...

background and aim: foundations and mechanisms of auditory scene analysis (asa) including segregation and integration were especially reviewed in the study. i focused on the related studies using event-related potentials (erps). recent findings: publications on asa using erps from 1971 to 2014 indicate neural mechanisms of asa in central auditory system. conclusion: asa results in recognition o...

Central auditory pathway maturation in children depends on auditory sensory stimulation. The objective of the present study was to monitor the cortical maturation of children with cochlear implants using electrophysiological and auditory skills measurements. The study was longitudinal and consisted of 30 subjects, 15 (8 girls and 7 boys) of whom had a cochlear implant, with a mean age at activa...