Evaluation the Effect of Chemotherapy Drugs and Thiosemicarbazone Complexes on Expression URHC CASC15 LncRNAs in Acute Lymphoblastic Leukemia Cell Line

nucleostemin (ns), a stem cell-abundant nucleolar protein, is critical for maintaining the self-renewal and proliferative properties of normal and cancerous stem cells. recent data suggests that ns signaling is important for proliferation of t-cells and leukemia cells. this study was conducted to verify the role of ns in pathogenesis and treatment of t-cell acute lymphocytic leukemia (t-all). o...

introduction: the majority of leukemia patients are acute leukemia patients, so that about 70.8% lymphoblastic leukemia were acute lymphoblastic leukemia (all) patients and 66.4 % of myeloid leukemia patients were acute myeloid leukemia (aml) in tehran metropolitan. during the last two decades, intensification of therapy by the use of high-dose cytarabine allogeneic stem cell transplantation in...

Introduction . Identical twins are a unique model that can be used to assess the concordance of various diseases, including acute leukemia. It should noted leukemia is characterized with high in cases monovular or placentas adhesion, which confirms development this disease prenatal period. Aim — present clinical case successful diagnosis and treatment lymphoblastic identical twins. Main finding...

Abstract Leukemia is a malignancy that affects the blood and bone marrow. Its detection classification are conventionally done through labor-intensive specialized methods. The diagnosis of cancer in children critical task requires high precision accuracy. This study proposes novel approach utilizing attention mechanism-based machine learning conjunction with image processing techniques for prec...

abstract the antineoplastic activities of alcoholic and aqueous extracts of the roots, stems and leaves of isatis campylocarpa an endemic species of the brassicaceae family from iran, investigated on the growth of jurkat as an acute lymphocytic leukemia cell line, k562 as a chronic myelogenous leukemia cell line and fen as a bladder cancer cell line using colorimetric assay. results showed that...

Background: Several studies have demonstrated the immunosuppresive effects of mes-enchymal stem cells (MSCs) in allogeneic or mitogenic interactions. Cell-cell contact inhibition and secretion of suppressive soluble factors have been suggested in this re-gard. Objective: To investigate if adipose derived MSCs could inhibit Jurkat lym-phoblastic leukemia T cell proliferation during coculture. Me...

The ferritin level, a protein responsible for iron metabolism and storage, is sensitive indicator of overload in various pathological conditions. In leukemia, levels increase with disease stages can predict survival after transplantation. Leukemia-induced dysregulation the ferroportin-hepcidin regulatory axis results intracellular accumulation, activation reactive oxygen species (ROS)-related s...