نتایج جستجو برای: cefpodoxime proxetil
تعداد نتایج: 268 فیلتر نتایج به سال:
CS-834 is a novel oral carbapenem antibiotic. This compound is an ester-type prodrug of the active metabolite R-95867. The antibacterial activity of R-95867 was tested against 1,323 clinical isolates of 35 species and was compared with those of oral cephems, i.e., cefteram, cefpodoxime, cefdinir, and cefditoren, and that of a parenteral carbapenem, imipenem. R-95867 exhibited a broad spectrum o...
CS-834 is a prodrug of the carbapenem R-95867, developed by Sankyo Co., Ltd., Tokyo, Japan. To investigate the possibility that CS-834 may be the first carbapenem usable in an oral dosage form, its in vitro antibacterial activity (as R-95867) and in vivo antibacterial activity were compared with those of cefpodoxime proxetil, cefditoren pivoxil, cefdinir, ofloxacin, imipenem, and amoxicillin. R...
In 1948 John Woodward successfully used chloramphenicol to treat patients with typhoid fever (TF )[1]. After this accomplishment, the first choice for the therapy of TF was chloramphenicol until the 1970s, when the first outbreaks of infection by antibiotic-resistant bacteria appeared. The loss of sensitivity by Salmonella typhi to the antibiotics used for the treatment of typhoid fever was not...
A simple, accurate and precise spectrophotometric method has been proposed for the determination of eleven cephalosporins, namely; cefaclor monohydrate, cefadroxil monohydrate, cefalexin anhydrous, cefradine anhydrous, cefotaxime sodium, cefoperazone sodium, ceftriaxone sodium, ceftazidime penthydrate, cefazolin sodium, cefixime and cefpodoxime proxetil in bulk drug and in pharmaceutical formul...
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