In Drosophila melanogaster, mesencephalic astrocyte-derived neurotrophic factor (DmMANF) is an evolutionarily conserved ortholog of mammalian MANF and cerebral dopamine neurotrophic factor (CDNF), which have been shown to promote the survival of dopaminergic neurons in the brain. We observed especially high levels of DmMANF in the visual system of Drosophila, particularly in the first optic neu...

Probabilistic model checking is a powerful formal verification method that can ensure the correctness of real-life systems that exhibit stochastic behaviour. The work presented in this thesis aims to solve the scalability challenge of probabilistic model checking, by developing, for the first time, fully-automated compositional verification techniques for probabilistic systems. The contribution...

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requires analytical methods that can (i) accurately monitor changes in the amount, nature, and dynamics of We used natural 13C abundance coupled with particle-size fractionSOM pools in natural and human-influenced systems ation to evaluate soil organic carbon (SOC) dynamics following deforand (ii) estimate C fluxes between the soils and atmoestation and subsequent cultivation in the subhumid Et...

1. Review of the literature ..........................................................................................1 1.1. Brain dopaminergic system ..................................................................................... 1 1.1.1. Development of the midbrain dopaminergic system ............................ 2 1.2. Parkinson’s disease...................................................

s from the 12th meeting of the International Society for Neural Transplantation and Restoration NeuroReport 2014, 25:139–163 Note from the Publisher The following abstracts section presents abstracts from all presenters at the 12th meeting of the International Society for Neural Transplantation and Restoration. They were meant to be included in last year’s December issue of NeuroReport, but unf...