نتایج جستجو برای: cd15
تعداد نتایج: 1069 فیلتر نتایج به سال:
The parasitic blood fluke Schistosoma mansoni synthesizes immunogenic glycans containing the human Lewis x antigen (Le(x); Galactose-β1-4(Fucα1-3)N-acetylglucosamine-β-R, also called CD15), but the biological role(s) of this antigen in the parasites and in humans is poorly understood. To develop IgG-based monoclonal antibodies (mAbs) specific for Le(x), we harvested splenocytes from S. mansoni-...
BACKGROUND Supratentorial primitive neuroectodermal tumor (sPNET) is a malignant brain tumor with poor prognosis. New model systems that replicate sPNET's molecular subtype(s) and maintain cancer stem cell (CSC) pool are needed. METHODS A fresh surgical specimen of a pediatric sPNET was directly injected into the right cerebrum of Rag2/SCID mice. The xenograft tumors were serially sub-transpl...
INTRODUCTION This study examines the expression of IL-17A-secreting cells within the inflamed synovium and the relationship to in vivo joint hypoxia measurements. METHODS IL-17A expression was quantified in synovial tissue (ST), serum and synovial fluid (SF) by immunohistochemistry and MSD-plex assays. IL-6 SF and serum levels were measured by MSD-plex assays. Dual immunofluorescence for IL-1...
Reactive immunoblastic proliferations can histologically mimic classical Hodgkin lymphoma (CHL), and show diffuse CD30 expression in large cells. The lack of expression of CD15 in a subset of CHL further complicates their separation from immunoblastic proliferations. Loss of expression of B-cell transcription factors is frequently exploited in making a diagnosis of CHL; however, the staining pa...
AML is a malignant disorder characterized by clonal expansion of immature myeloid hematopoietic stem cells, myeloblasts, in bone marrow, blood and/or other tissue. Despite advances in treatment the majority of patients eventually die from this aggressive disease. We conducted a study including 9,729 AML patients diagnosed in Sweden 1973-2005 to define survival patterns over time. One-year relat...
The roles of myeloid‑derived suppressor cells (MDSCs) and regulatory T‑cells (Tregs) in acute myocardial infarction (AMI) remain elusive. present study aimed to analyze the proportions granulocytic monocytic populations MDSCs (G‑MDSCs M‑MDSCs, respectively), Tregs peripheral blood mononuclear (PBMCs) patients with AMI. recruited 34 AMI 37 healthy controls without clinical signs ischemia. PBMCs ...
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