Recent genome-wide association studies have rapidly improved our understanding of the molecular pathways leading to inflammatory bowel disease (IBD), which includes Crohn's disease (CD) and ulcerative colitis (UC). Although several reports have demonstrated that gene single nucleotide polymorphisms (SNPs) are associated with susceptibility to IBD, its precise genetic factors have not been fully...

Abbreviation AFP Alpha fetoprotein CD Cluster of differentiation CEA Carcino-embryonic antigen CHOP Cyclophosphamide, hydroxydaunorubicin (also called doxorubicin or Adriamycin), Oncovin (vincristine), prednisone CT Contrast tomography DLBCL Diffuse large B-cell lymphoma NHL Non-Hodgkin lymphoma IHC Immunohistochemistry MPO Myeloperoxidase LCA Leucocyte common antigen PV Per vagina PAP Papanico...

Submit Manuscript | http://medcraveonline.com Abbreviations: NDV: Newcastle Disease Virus; APMV-1: Avian Paramyxovirus Type I; IFN: Interferon; CTLA-4: Cytotoxic T Lymphocyte Associated Antigen-4; RCC: Renal Cell Carcinoma; HNSCC: Head and Neck Squamous Cell Carcinoma; IL-2: Interleukin-2; DTH: Delayed Type Hypersensitivity; Gy: Gray; BCG: Bacillus Calmette-Guerin; HN: Hemagglutinin-Neuraminida...

Coeliac disease (CD) is one of the most common diseases worldwide, resulting from a combination of environmental (gluten) and genetic (human leucocyte antigen (HLA) and non-HLA genes) factors. Depending on the geographical location, the prevalence of CD has been estimated to approximate 0.5-1%. The only treatment currently available for CD is a gluten-free diet (GFD) excluding gluten-containing...

background: the aim of this study was to evaluate the possible use of biomphalaria alexandrina snail antigens in diagnosis of schistosomiasis mansoni using enzyme linked immunolectrotransfere blot (eitb). methods: s. mansoni adult worm crude antigens (awa), feet and visceral humps of b. alexandrina and bulinus truncatus were used. hyperimmune mice sera (his) versus each antigen were prepared fo...

Celiac disease (CD) is most probably an immunological disease, precipitated in susceptible individuals by ingestion of wheat gliadin and related proteins from other cereals. The disease shows a strong human HLA association predominantly to the cis or trans encoded HLA-DQ(alpha 1*0501,beta 1*0201) (DQ2) heterodimer. T cell recognition of gliadin presented by this DQ heterodimer may thus be of im...

coeliac disease (cd) is an autoimmune disorder which leads to chronic inflammation of the gut. untreated cd is associated with upper gastrointestinal malignancies, small-bowel lymphoma and adenocarcinoma are recognized complications of untreated coeliac disease (cd). we report the case of a 43-year-old male suffering from cd who was treated with a gluten-free diet one year,  presenting with com...

The outer membrane protein CD of Moraxella catarrhalis is considered to be a potential vaccine antigen against Moraxella infection. We purified the native CD from isolate O35E, administered it to mice, and detected considerable titers of anti-CD antibodies. Anti-CD sera were cross-reactive towards six different M. catarrhalis isolates and promoted bacterial clearance of O35E in a pulmonary chal...

background: celiac disease (cd) is an immune mediated condition that leads to small bowel atrophy that resolves with a gluten free diet (gfd). extra-intestinal manifestations of cd include hypertransaminasemia. in this study, the effects of a gfd on hypertransaminasemia in patients with newly diagnosed cd were studied. methods: ninety eight new diagnosed consecutive patients with cd 40 males an...