background: neuropathic pain (np) is a serious suffering medical condition that frequently leads to disability and life style changes. although the exact mechanisms of np are still unknown, recently the role of reactive oxygen species (ros) reported as an important factor for np. apoptosis, increase of atp production and reduction of antioxidants are also the other factors influencing in np. th...

The mitigation of co-channel interference (CCI) and inter-symbol interference (ISI) has been a major area of focus of researchers in wireless communications. An approach of interest separates CCI cancellation and ISI equalization in a slow frequency-selective Rayleigh fading channel into two stages. A space-time filter reduces the CCI, followed by a Viterbi equalizer for ISI equalization. The c...

In this paper, system capacity of the reverse link of a wireless multimedia CDMA system with transmission power control is analysed for receivers with and without CCI cancellers. For N classes of users, system capacity is represented by a point in an N-dimensional space. It is shown that system capacity is improved considerably with CCI cancellers, that system capacity region is non-convex in g...

This study was designed to investigate the therapeutic effects of saffron (Crocus Sativus L) and its main constituent crocin on neuropathic pain behavioral responses induced by chronic constriction injury (CCI) in rats. Adult male Wistar rats (200 to 250 g) were randomly assigned into 5 groups: Sham + saline, CCI + saline, CCI+ saffron (30 mg/kg), CCI +crocin (15 mg/kg) and CCI + crocin (30 mg/...

This study describes the application of CCI (Control/Compensation Index) [3, 4] to a corpus of spontaneous Beijing Chinese. CCI is a modification of the PVI algorithm [8], devised to provide an improved representation of the rhythmic tendencies of natural languages. The CCI algorithm was previously applied to the modeling of Italian [3, 5]. The present findings refer to Beijing Chinese.

Release of large amounts adenosine triphosphate (ATP), a gliotransmitter, into the extracellular space by traumatic brain injury (TBI) is considered to activate microglia followed release inflammatory cytokines resulting in excessive response that induces secondary injury. The present study investigated whether antagonists ATP receptors (P2X4 and/or P2X7) on are beneficial for reducing post‑inj...

Clinical data have shown that chronic exposure to stress may be accompanied by an enhancement of inflammation-related pain sensitivity. In this context, little is however known on the impact of stress on neuropathic pain. In the present study we addressed this issue by combining the chronic constriction injury (CCI) model with an ongoing social stress (OSS) paradigm. Cold plate and von Frey tes...

Internal jugular vein (IJV) compression has been shown to reduce axonal injury in pre-clinical traumatic brain injury (TBI) models and clinical concussion studies. However, this novel approach to prophylactically mitigating TBI through venous congestion raises concerns of increasing the propensity for hemorrhage and hemorrhagic propagation. This study aims to test the safety of IJV compression ...

Objectives Several lines of evidence showed that minocycline possesses antioxidant and anti-inflammatory properties. This study aimed to demonstrate the effects of minocycline in rats subjected to chronic constriction injury (CCI). Materials and Methods In this study four groups (n = 6-8) of rats were used as follows: Sham, CCI, CCI + minocycline (MIN) 10 mg/Kg (IP) and CCI + MIN 30 mg/Kg (IP...