the present paper offers a meso-scale numerical model to investigate the effects of random distribution of aggregate particles and steel fibers on the elastic modulus of steel fiber reinforced concrete (sfrc). meso-scale model distinctively models coarse aggregate, cementitious mortar, and interfacial transition zone (itz) between aggregate, mortar, and steel fibers with their respective materi...

We have previously shown that the decrease in large artery distensibility observed in patients with essential hypertension (HT group) was primarily due to an increase in distending pressure and not to hypertension-associated structural modifications of the artery, suggesting a functional adaptation of the wall material. To evaluate the elastic properties of the wall material of the common carot...

OBJECTIVE To determine whether arterial wall hypertrophy in elastic arteries was associated with alteration in their mechanical properties in young patients with Williams syndrome. METHODS Arterial pressure and intima-media thickness, cross sectional compliance, distensibility, circumferential wall stress, and incremental elastic modulus of the common carotid artery were measured non-invasive...

background: the aim of this study was to compare the effects of conventional acid etching and laser etching on the nano-mechanical properties of the dental enamel using nano-indentation test. materials and methods: in this experimental in vitro study, buccal surfaces of 10 premolars were divided into three regions. one of the regions was etched with 37% phosphoric acid and another etched with e...

With progressing age, large arteries diminish their longitudinal stretch, which in extreme cases results in tortuosity. Increased age is also associated with loss of vessel distensibility. We measured pressure-diameter curves from muscular porcine carotid arteries ex vivo at different longitudinal stretch ratios (lambda(z) = 1.4 and 1.8) and under different vascular smooth muscle (VSM) conditio...

The effect of differentiation on the transverse mechanical properties of mammalian myocytes was determined by using atomic force microscopy. The apparent elastic modulus increased from 11.5 +/- 1.3 kPa for undifferentiated myoblasts to 45.3 +/- 4.0 kPa after 8 days of differentiation (P < 0.05). The relative contribution of viscosity, as determined from the normalized hysteresis area, ranged fr...

BACKGROUND Exposure to risk factors in childhood may have long-term influences on vascular function. We examined the relationship between risk factors identified in childhood and arterial elasticity assessed in adulthood. METHODS AND RESULTS Carotid artery compliance (CAC), Young's elastic modulus (YEM), and stiffness index (SI), 3 measures of large-artery elasticity, were assessed with nonin...

To the Editor: We have read the recent letter by Hermeling et al. entitled “Potentials and Pitfalls of Local PWV Measurements,”1 discussing the advantages and challenges for local pulse wave velocity (PWV) measurements. The letter was in reference to an article by Vappou et al. regarding pulse wave imaging measurement of arterial stiffness in vivo.2 In the common carotid artery, due to the susc...

UNLABELLED Although significant advances have been made in understanding the molecular mechanisms that influence tongue squamous cell carcinoma (TSCC) metastasis, less is known about the association between the cellular elastic modulus and TSCC metastasis. Atomic force microscopy (AFM) nanoindentation via the rate-jump method was used to detect the elastic modulus of TSCC cells from patients an...

The high blood rate that often occurs in arteries may play a role in artery failure and tortuosity which leads to blackouts, transitory ischemic attacks and other diseases. However, vibration and instability analysis of carotid arteries are lacking. The objective of this study is to investigate the vibration and instability of the carotid arteries conveying blood under axial tension with surrou...