We analyzed the clinical profiles and autopsy findings of five patients who died shortly after developing cerebral infarction following thrombotic occlusion of the internal carotid artery. In all five cases, thrombotic occlusion was caused by rupture of the fibrous lining over the gruel of atheroma at the origin of the internal carotid artery showing tight stenosis of the lumen. The mean +/- SD...

Fig. 1. Perfusion CT scan showing extensive perfusion defects in the bilateral carotid territories and whole brainstem (arrow). Extensive deficits of cerebral blood flow (CBF) and cerebral blood flow volume (CBV) represent a large ischemic core in the bilateral hemispheres and brainstem. Fig. 2. CT angiogram showing tapered occlusions of both internal carotid arteries and occlusion of the basil...

BACKGROUND AND PURPOSE The purpose of this study was to prospectively investigate the contribution of the ipsilateral external carotid artery (ECA) to cerebral perfusion in patients with internal carotid artery occlusion. METHODS Institutional Review Board approval and informed consent were obtained. Thirty functionally independent patients (24 men, 6 women; mean age, 63 years) with an angiog...

The authors of the preceding reports [1-3] are to be commended for their efforts to solve a problem that has plagued medicine for almost 1 00 years, that is, the need to know if it would be safe to sacrifice the carotid artery. Struggling with this problem has been frustrating. The experience of having a patient undergo successful carotid test occlusion and subsequent permanent occlusion, only ...

Background and Purpose—Tandem internal carotid and middle cerebral artery occlusion independently predicts poor outcome after intravenous thrombolysis. Recanalization of internal carotid artery dissection by stent-assisted angioplasty has recently been proposed when anticoagulation fails to prevent a new ischemic event. We recently reported a case of tandem internal carotid and middle cerebral ...

Doppler ultrasound was used to detect possible flow changes in the carotid arteries of patients with central retinal artery and vein occlusion. Twenty-three patients with central retinal artery occlusion (mean age 56, SD 11, years) were examined 4 to 48 months after the development of the occlusion and compared with age and sex matched control subjects with no history of any disease known to be...

This study correlates the appearance of the cavernous segment of the carotid artery on MR images with the presence of significant stenosis or occlusion of the cervical carotid artery as seen on angiograms in 100 patients who had brain MR imaging and arteriography within a 1-week period. Four patients demonstrated isointense signal within the carotid artery's cavernous segment; two of these find...

Background & Aims: Ischemic postconditioning, conducted by a series of brief occlusion and release of the bilateral common carotid arteries, has neuroprotective properties in permanent or transient models of middle cerebral artery (MCA) occlusion but its delayed neuroprotective effects in the embolic model of stroke, especially in female rat, have not yet been reported and were investigated ...

BACKGROUND Reopening of an occluded internal carotid artery (ICA) is often seen in dissections but only rarely occurs in atherothrombotic occlusion of the internal carotid artery. CASE DESCRIPTION A 60-year-old man suffered a minor stroke with dysphasia in March 1995. Color-coded duplex ultrasonography of his neck arteries revealed a left ICA occlusion. He was placed on a regimen of aspirin a...