Cancer of the cervix is a significant public health problem globally, especially in developing countries where it is the most common cancer in women. The psychological impact of cervical cancer is also significant. Each patient experience a range of practical, psychological and emotional challenges as a result of their diagnosis and treatment related adverse effects. In early stages it may be t...

Background: In India, cervical cancer is the single largest killer of middle-aged women, followed by breast cancer. Though the effective screening test is available, most of the women in developing and underdeveloped countries do not have access to Pap (papanicolou) smear screening due to poor literacy and low level of awareness both early detection and screening remain a major area of concern ...

Graphical abstract Abstract The phenomenal extracellular matrix (ECM) remodelling of the cervix that precedes myometrial contraction labour at term or preterm appears to share some common mechanisms with occurrence, growth, invasion and metastasis cervical carcinoma. Matrix metalloproteinases (MMPs) are zinc-dependent endopeptidases pivotal complex tissue modulation includes degradation, exchan...

For many decades, the epidemiological finding of females who have cervical cancer was identified as being suggestive of a sexually transmitted process and many biological agents were proposed as being responsible. In order to understand the contributions of epidemiological and laboratory methods to identifying cervical cancer etiology, this paper aimed to provide an historical review of the acc...

INTRODUCTION Uterine cervix cancer is an important public health problem in Tunisia. In this study, we report trends in the incidence of adenocarcinoma and squamous cell carcinoma of the cervix uteri in the central region of Tunisia during 1993-2006. DESIGN Data were obtained from the Cancer Registry of the Center of Tunisia which registers invasive cancer cases by active methods. Five-year a...

Cancer of the uterine cervix is the 5th most deadly type of female cancer [1]. It is clearly demonstrated that HPV infection is the necessary, but not the sufficient cause of most cervical cancers [2]. The association between cancer of the uterine cervix and HPV is unique because no other human cancer is dependent on a single infectious factor for its development [3]. Worldwide, HPV types 16 an...

Background: Cervical cancer is the fourth leading cause of death in females worldwide. In India cervical morbidity and mortality. Cancer cervix preventable, can be diagnosed at pre-malignant stage with adequate repetitive cytological screening by Papanicolaou (Pap) smears. Aim this study was to role Pap smear detecting premalignant malignant lesions as well non-neoplastic cervix. Methods: It a ...

Gynecologic malignancies may have similar histological characteristics. This may lead to difficulties in determining the origin of the cancer and to distinguish a synchronous neoplasm from a metastatic cancer in advanced cases. Recently, we treated a 59-year-old patient with adenocarcinoma of the uterine cervix, endometrium, fallopian tubes, and ovaries. It was difficult to determine whether th...