نتایج جستجو برای: cancer activity
تعداد نتایج: 1961890 فیلتر نتایج به سال:
soybean isoflavone genistein has multiple anticancer properties and its pro-apoptotic and anti-proliferative effects have been studied in different cancer cells. however, the mechanisms of action of genistein and its molecular targets on human colon cells have not been fully elucidated. therefore, caspase-3 and p38 mitogen-activated protein kinase (p38 mapk) as the main therapeutic targets were...
Background: One of the medicinal fungi that has been used in traditional medicine for a long time is the Basidiomycete fungus Fomes fomentarius, which is widely distributed in Iran. Polysaccharides as one of the metabolites of this fungus have anti-inflammatory, anti-diabetic, antibacterial, antioxidant, and anti-cancer properties. Materials & Methods: Optimization of independent variable...
Breast cancer is the most common cancer type among women all over the world. Chemotherapy is the use of anticancer medicines for treating cancer but it has many side effects and cells may become resistant to these chemical medicines. Therefore, finding new compounds of natural origin could be a promising solution to this problem. The aim of the current study was to evaluate anticancer activity ...
conclusions according to this observation, another factor such as oncogenes activity may cause cancer in samples but ct genotype of mthfr can be considered as an effective factor in creating cancer. results methylation status of e-cadherin gene numbers of methylated cases in the cancer group were equal to one and unmethylated cases equal to 33 and numbers of unmethylated cases in the non-cancer...
conclusions recent treatment, in addition to age, gender and daylight duration were proved as strong independent determinants on bat development and the level of metabolic activity at [18 f] dg pet/ct and should be considered as an important confounding factor in future researches. results one-hundred eighteen studies were recognized to demonstrate foci of fdg bat uptake (3.1%, mean age: 22.7 y...
Background & Aims: Malignant neoplasm of the colon wall or colon cancer (or colorectal cancer) is the fourth and third most common cancer in men and women worldwide, respectively. Risk factors for colon cancer are complex and the drug therapies did not have a great survival chance. Regarding the probable role of the physical activity in preventing the incidence and severity of cancer, the prese...
Introduction: Both physical inactivity and breast cancer incidence have increased dramatically during the last two decades in Iranian women. The purpose of this study was to investigate the association of physical activity with breast cancer incidence in premenopausal women. Methods: In this case-control study, which was performed from March 2017 to May 2018, 150 incident cases with histologica...
background: telomerase activity increases in cancer cells. bcl-2 is an antiapoptotic factor that its concentration grows in many cancer cells including hepatocellular carcinoma cells. in this study, an attempt was made to investigate the effects of a new synthetic compound, platinum azidothymidine (pt-azt) on treatment of rats with hepatocellular carcinoma (hcc) and to compare its effects with ...
objective(s): gastric cancer is the first and second leading cause of cancer related death in iranian men and women, respectively. gastric cancer management is based on the surgery, radiotherapy and chemotherapy. in the present study, for the first time, the beneficial effect of saffron (crocus sativus l.) aqueous extract (sae) on the 1-methyl-3-nitro-1-nitrosoguanidine (mnng)-induced gastric c...
Background & Objective: Cancer metastasis is the primary cause of cancer morbidity and mortality, it accounts for about 90% of cancer deaths. Cancer treatment has improved significantly, due to early detection and inhibition of cancer growth. The ability to invade and migrate is important in malignant tumor cells. The study of cell migration is valuable in cancer diagnosis, prognosis, drug dev...
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