The aim of this study was to determine the effectiveness of antibiotic-impregnated implants in the prevention of bone infection. We used a model of contaminated fracture in goats to evaluate four treatment groups: no treatment, hand-made tobramycin-impregnated polymethylmethacrylate beads, commercially-available tobramycin-impregnated calcium sulphate pellets and commercially-available tobramyc...

The bacterial strain producing thermostable, alklophilic alpha-amylase was identified as Bacillus amyloliquefaciens KCP2 using 16S rDNA gene sequencing data (NCBI Accession No: KF112071). Medium components were optimized through the statistical approach for the synthesis of alpha-amylase by the organism under solid-state fermentation using wheat bran as the substrate. The medium components infl...

A young man developed acute renal failure and hypercalcaemia following severe burns. The hypercalcaemia was initially controlled by haemodialysis, but it persisted after return of renal function. Plasma PTH was inappropriately elevated, but the nephrogenous cyclic adenosine monophosphate level was low; thus the PTH was probably not biologically active, and may have been artefactually elevated b...

This study compares the chemical composition of rainwater samples collected at two sampling sites, the first situated in the Rijeka city centre and the second in a suburban site 120 m above the sea level. The rainwater samples were analysed for precipitation weighted average concentrations of hydrogen, sulphate, nitrate, chloride, ammonium, sodium, potassium, calcium, and magnesium. The results...

Magnesium sulphate has well known antiplatelet properties. Its effect on leptin-dependent platelet aggregation has not been studied previously. Thus, we performed this ex vivo study to investigate whether magnesium sulphate is able to inhibit leptin-dependent aggregation of human platelets. We obtained platelet rich plasma (PRP) from venous blood samples of 16 healthy male volunteers, and we me...

Objective. The aim of this study was to evaluate the rat subcutaneous tissue reaction to calcium hydroxide-based intracanal medicaments, UltraCal XS (calcium hydroxide, barium sulphate, aqueous matrix), Hydropast (calcium hydroxide, barium sulphate, and propyleneglycol), and Calen (Calcium hydroxide, zinc oxide, colophony, and polyethyleneglycol), used as a control. Methods. Forty-eight rats (R...

Infected nonunion of long bones may require intravenous antibiotics over a lengthy period which may result in a high rate of complications. This study aims to assess the efficacy of local antibiotics used as a replacement to prolonged intravenous therapy. Thirteen patients with infected nonunion of long bones who failed at least one previous surgery were included. The infection was treated thro...

Natural stone is an important component of historical heritage (buildings and art objects such as sculptures or rock engravings), it still widely used in contemporary works. Soluble salts are the main erosive agent built environment, we review here comparative studies that subject same type to testing with different salt solutions. The results mostly support accepted notion major impact sodium ...

Background & Aim:  The hot water extract of a mixture of Anogeissus leiocarpus and Prosopis africana is widely used in the northern part of Nigeria for the treatment and management of asthma. Since investigations of its pharmacological activities already justify its use, and the need for standardization of herbal medicine and develop appropriate dosage forms has continued to g...

INTRODUCTION: Many bone graft substitutes have become available to assist in increasing healing rates and decrease donor site morbidity resulting from orthopaedic procedures. Calcium sulfate is a widely used bone graft substitute, and is now available as a bone void filler as well as in pellets. We wished to examine: 1. The effect of a solid calcium sulphate cylinder in an intercalary defect in...