The Joint Transportation Research Program serves as a vehicle for INDOT collaboration with higher education institutions and industry in Indiana to facilitate innovation that results in continuous improvement in the planning, design, construction, operation, management and economic efficiency of the Indiana transportation infrastructure. NOTICE The contents of this report reflect the views of t...

In some earlier papers (I , 2, 3) on the production of peritoneal transudates in rabbits by the intravenous infusion of large quantities of sodium chloride solution or of mixtures of a sodium chloride and calcium chloride solution, or of these solutions with the addition of adrenalin, we found that both calcium chloride and adrenalin increased the amount of peritoneal transudate. We pointed out...

PTH stimulates transcellular Ca2+ absorption in renal distal convoluted tubules. The effect of PTH on membrane voltage, the ionic basis of the change in voltage, and the relations between voltage and calcium entry were determined on immortalized mouse distal convoluted tubule cells. PTH (10(-8) M) significantly increased 45Ca2+ uptake from basal levels of 2.81 +/- 0.16 to 3.88 +/- 0.19 nmol min...

Calcium-activated chloride channel regulator 1 (CLCA1) activates calcium-dependent chloride currents; neither the target, nor mechanism, is known. We demonstrate that secreted CLCA1 activates calcium-dependent chloride currents in HEK293T cells in a paracrine fashion, and endogenous TMEM16A/Anoctamin1 conducts the currents. Exposure to exogenous CLCA1 increases cell surface levels of TMEM16A an...

High cation diets can cause milk fever in dairy cows as they induce a metabolic alkalosis reducing the ability of the cow to maintain calcium homeostasis at the onset of lactation. Adding anions to the diet can offset the effect of the high cation forages by inducing a mild metabolic acidosis, restoring the ability to maintain calcium homeostasis. The difference in mEq of dietary cations and an...

The aim of the study was to generate rules for the prediction of the chloride resistance of concrete modified with high calcium fly ash using machine learning methods. The rapid chloride permeability test, according to the Nordtest Method Build 492, was used for determining the chloride ions' penetration in concrete containing high calcium fly ash (HCFA) for partial replacement of Portland ceme...

The effects of salinity and supplied calcium chloride on growth and leaf ions concentration of tomato (Lycopersicon esculentum L.) were investigated in Gorgan, Iran. A factorial experiment was conducted based on RCBD with four NaCl levels (0, 50, 100, and 150 mM) and four CaCl2 levels (0, 100, 200 and 300 mg L-1). Data of growth, yield and leaf’s Ca, K, and Na content were subjected to analyze ...

Atenolol, a selective beta(1)-adrenergic antagonist, is commonly used to treat hypertension, ischemic heart disease and cardiac dysrhythmias. Few cases of severe atenolol intoxication have been described, and only one of these reports discussed the use of calcium chloride as a treatment. We present a case of atenolol overdose associated with shock and first-degree heart block, in which administ...

OPERATION of a nervous mechanism in the genesis of cardiac arrhythmias secondary to the injection of calcium chloride was suggested by the observation that electrical sympathetic stimulation consistently induced ventricular arrhythmias only when calcium chloride was given simultaneously. Insight into the problem was obtained when sympatholytic and other autonomic blocking drugs were reported to...