OBJECTIVES To examine whether the gender difference in coronary artery calcification, a measure of atherosclerotic plaque burden, is lost in type 1 diabetic patients, and whether abnormalities in established coronary heart disease risk factors explain this. BACKGROUND Type 1 diabetes abolishes the gender difference in coronary heart disease mortality because it is associated with a greater el...

BACKGROUND Cardiovascular calcification, including arterial intimal and medial calcification (AIC and AMC) and valvular calcification (VC) are important predictors of outcome in chronic dialysis patients. We aimed to compare their prevalence and analyze respective risk factors in hemodialysis (HD) patients. METHODS A total of 81 HD patients were enrolled. Vascular calcification was assessed b...

Renal failure is associated with aortic valve calcification. Using our rat model of uremia-induced reversible aortic valve calcification, we assessed the role of apoptosis and survival pathways in that disease. We also explored the effects of raloxifene, an estrogen receptor modulator, on valvular calcification. Gene array analysis was performed in aortic valves obtained from three groups of ra...

BACKGROUND Pyrophosphate (PPi) is a potent inhibitor of vascular calcification and may be deficient in renal failure. We sought to determine whether plasma PPi is affected by dialysis or the mode of dialysis and whether it correlates with vascular calcification. METHODS PPi was measured in plasma samples stored from a recent study of vascular calcification in 54 HD patients, 23 peritoneal dia...

Inflammatory response and calcification are strongly implicated in osteoarthritis (OA) progression. Key inflammatory biomarkers present throughout the process of OA have been established but an association with calcification has not been clarified. A faint line, tidemark, exists between the subchondral bone and the articular surface in knee joints that is presumed to be the line of demarcation ...

BACKGROUND Metastatic pulmonary calcification, a complication of uraemia and disordered calcium metabolism, may be diffuse or localised. The factors that determine calcium precipitation are complex, but tissue alkalosis is thought to be important. As obstruction of the pulmonary artery theoretically causes local alkalosis a retrospective necropsy study was carried out to examine the relation be...

Sharks are often found in all the waters scattered various regions of world. On other hand, shark fisheries have declined globally due to fishing as well demand is very high. The length-frequency distribution for Carcharhinus sorrah distributed between 33-131 cm falciformis 51-161 cm. length-weight relationship allometric negative, while on positive. maturity level august Full Classification (F...

Calcific aortic valve disease (CAVD) is a progressive pathology characterized by calcification mainly within the cusps of the aortic valve (AV). As CAVD advances, the blood flow and associated hemodynamics are severely altered, thus influencing the mechanical performance of the AV. This study proposes a new method, termed reverse calcification technique (RCT) capable of re-creating the differen...

The present experiments investigate medial artery calcification in adult rats made uremic by feeding a synthetic diet containing 0.75% adenine for 4 weeks. Calcification was assessed by Alizarin red staining of intact aortas, by von Kossa staining of carotid artery sections, and by calcium and phosphate incorporated into the thoracic aorta. The major conclusions are as follows: Lowering the pro...