Problem statement: Cadmium is highly toxic at low concentrations, but the mechanism of its toxicity is still not understood particularly at the cellular and subcellular level. Approach: In this study we examined the effects of cadmium on the oxidophosphorylation properties of mitochondria isolated from potatoes. Results: Cadmium strongly disturbed the respiratory metabolism of mitochondria isol...

P2X receptors are ATP-gated cation channels consisting of three subunits that are mutually intertwined and form an upper, central, and extracellular vestibule with three lateral portals and the channel pore. Here we used cysteine and alanine scanning mutagenesis of the rat P2X4R receptor V47-V61 and K326-N338 sequences to study structural and functional properties of extracellular vestibule dur...

Cadmium pollution of the environment has become a serious problem due to the increasing consumption of cadmium by industry in the past 20 years. Cadmium is introduced into the environment from the effluence of electroplating industry, and in solid and aqueous dis‐ charges from mining operations. Increased environmental awareness has resulted in the promulgation of more stringent legislation in ...

Mitochondria from rat liver were isolated in 0.25 M sucrose according to Schneider (5) and suspended in 1 ml. of 0.25 M sucrose per gm. of fresh liver. Rabbit liver mitochondria, used only for the experiments in Table I, were prepared by grinding the tissue in 0.25 M sucrose in a Waring blendor at reduced speed (6) and were suspended in 1 ml. of sucrose solution per 2 gm. of liver. The reaction...

Although most animals with scrotal testes are susceptible to cadmium-induced testicular toxicity, strain-related differences are seen in mice. Resistant murine strains demonstrate a decreased cadmium concentration in the testis and also in the epididymis and seminal vesicle. In this study we analyzed cadmium transport into tissues with a vascular barrier, the testis, epididymis, and brain, in a...

The use of plants for rehabilitation of heavy-metal-contaminated environments is an emerging area of interest because it provides an ecologically sound and safe method for restoration and remediation. Although a number of plant species are capable of hyperaccumulation of heavy metals, the technology is not applicable for remediating sites with multiple contaminants. A clever solution is to comb...

Toxicity of cadmium to Folsomia candida was determined in soils at different pHs (3.5, 5.0, and 6.5). The Langmuir sorption constant (K(L)), based on pore-water or water-extractable concentrations, showed a pH-related increase of cadmium sorption that was most pronounced when using free Cd2+ ion activities ([Cd2+]s). Two-species Langmuir isotherms that used total cadmium concentration ([Cd]) or...

Radiation detectors for medical imaging at room temperature have been developed thanks to the availability of large chlorine-doped cadmium telluride (CdTe:Cl) crystals. Microstructural defects affect the performance of CdTe:Cl radiation detectors. Advanced characterization tools, such as Ion Beam Induced Current (IBIC) measurements and chemical etching on tellurium and cadmium faces were used t...

heavy metal accumulation in plants causes induction of oxidative stress. plants have severaldefense systems involved in detoxifying free radicals. in the present research we treated the 15 d.seedlings of b. napus grown in pots with different concentrations of cadmium (0, 10, 50 and 100 μm) ascdcl2. after 3 weeks we measured malondealdehyde (mda) content in leaves of treated plants as anindicati...