Metals differ from most synthetic organic chemicals in that their clinical manifestations are well known and methods for their measurement in the body are generally well established. Since metals are ubiquitous, special care should be taken to identify the source, whether dump site or not. Isotopic ratios may be used for lead. Time of exposure may be highly variable so estimates will be necessa...

results approximately 20% of the patients expressed alternatively spliced transcripts of gla mrna involving exon 3. we additionally report that such non-canonical transcripts are physiologically expressed at trace levels in healthy individuals, and that their expression in leukocytes markedly increased in blood samples kept at room-temperature for 48 hours before rna extraction. background defi...

Objective and Study Design: The present study has been undertaken to evaluate the protective efficacy of lycopene on cadmium induced toxicity in heart of albino mice. Materials and Methods: 24 Albino mice were divided into four groups. Group I mice were kept as control. Group II animals were administered a single dose of cadmium chloride (0.32mg/kg bw) intraperitoneally. Group III animals were ...

Published studies in which rats were exposed to CdCl2 in standard chow or drinking water were analyzed to compare the relative bioavailability of cadmium from the two media. Relative bioavailability was assessed from estimates of the rate of accumulation of cadmium in kidney cortex or liver. Data were grouped into tiers based on study design and reporting of data: Tier 1, identical experimental...

oxygen consumption (VO2), diminished with age. Older subjects had a lower resting cardiac output (Q) than normal subjects, but an identical increase in Q with Vo,. There was no evidence of flattening of this curve as the older subjects approached highest exercise loads. Consequently, the arteriovenous oxygen difference did not increase abnormally on high loads, and the cardiac response to exerc...

oxygen consumption (VO2), diminished with age. Older subjects had a lower resting cardiac output (Q) than normal subjects, but an identical increase in Q with Vo,. There was no evidence of flattening of this curve as the older subjects approached highest exercise loads. Consequently, the arteriovenous oxygen difference did not increase abnormally on high loads, and the cardiac response to exerc...

This study was undertaken to explore the effects of chronic low-level cadmium ingestion in Dahl hypertension-resistant (R) and hypertension-sensitive (S) lines of rats. Groups of weanling female R and S rats were given 0 or 1 mg cadmium/1. in drinking water and fed either a low salt (0.4% NaCl) or a high salt (4% NaCl) diet for 28 weeks. Cadmium produced hypertension associated with gross cardi...

abstract background: fisheries safety control and considering heavy metal accumulation is one of the most important factors in maintaining health society and assuring the safety of this valuable food. the purpose of this study is evaluating the potential of bioaccumulation and exposure to lead and cadmium due to consumption of penaeus semisulcatus in tehran city 2012.. methods: samples were col...

The aim of the present study was to investigate the association between cadmium body burden and the areas of exposure in Thailand, as well as blood pressure levels, the types and frequencies of foods, and alcohol consumption. A total of 182 healthy adult Thai subjects of both genders (89 males, 93 females) ages 18 to 57 years old weighing 40-95 kg were included in this study. Participants were ...