Kargacin, Gary J., Zenobia Ali, Shi-Jin Zhang, Natashka S. Pollock, and Margaret E. Kargacin. Iodide and bromide inhibit Ca uptake by cardiac sarcoplasmic reticulum. Am J Physiol Heart Circ Physiol 280: H1624–H1634, 2001.—Recent studies indicate that the Ca permeability of the sarcoplasmic reticulum (SR) can be affected by its anionic environment. Additionally, anions could directly modulate th...

This paper presents results of hydro-chemical processes controlling groundwater chemical composition, using an integrated application of hierarchical cluster analysis and factor analysis of a major ion data set of groundwater from Mighan playa aquifer. Cluster analysis classified samples into four clusters(A, B, C and D) according to their dominant chemical composition: cluster A (dominant comp...

Abstract Appraisal of groundwater fitness to drinking, agricultural, and domestic purposes was attempted within the Thiruvallur district South India since is significant sources for above utilities. Groundwater samples collected from a sum 110 locations have be analyzed major concentrations which higher values total dissolved solids (TDS), chloride (Cl − ), sodium (Na + ) ions were noted during...

Extracellular ATP regulates bile formation by binding to P2 receptors on cholangiocytes and stimulating transepithelial Cl(-) secretion. However, the specific signaling pathways linking receptor binding to Cl(-) channel activation are not known. Consequently, the aim of these studies in human Mz-Cha-1 biliary cells and normal rat cholangiocyte monolayers was to assess the intracellular pathways...

Recent studies indicate that the Ca(2+) permeability of the sarcoplasmic reticulum (SR) can be affected by its anionic environment. Additionally, anions could directly modulate the SR Ca(2+) pump or the movement of compensatory charge across the SR membrane during Ca(2+) uptake or release. To examine the effect of anion substitution on cardiac SR Ca(2+) uptake, fluorometric Ca(2+) measurements ...

The active site for water oxidation in photosystem II goes through five sequential oxidation states (S(0) to S(4)) before O(2) is evolved. It consists of a Mn(4)Ca cluster close to a redox-active tyrosine residue (Tyr(Z)). Cl(-) is also required for enzyme activity. To study the role of Ca(2+) and Cl(-) in PSII, these ions were biosynthetically substituted by Sr(2+) and Br(-), respectively, in ...

Mammary gland ion transport is essential for lactation and is regulated by prolactin and glucocorticoids. This study delineates the roles of prolactin receptors (PRLR) and long-term prolactin and dexamethasone (P-D)-mediation of [Ca(2+)](i) and Cl(-) transport in HC-11 cells. P-D (24 h) suppressed ATP-induced [Ca(2+)](i). This may be due to decreased Ca(2+) entry since P-D decreased transient r...