Vietnam's sea is assessed to be very diverse and rich in seaweed species. It about 1000 different species of seaweed, which more than 800 have been identified, classify into genus, families, classes, phylums, continuously updated from the 1950s present. Previous studies by Vietnamese international scientists shown that lipids contain many valuable active ingredients such as acids C20: 4n-6 (AA)...

OBJECTIVE Previous studies indicated a difference in crosstalk between canonical WNT pathway and nuclear factor-κB (NFκB) signaling in human and animal chondrocytes. To assess whether the differences found were dependent on cell types used, we tested the effect of WNT modulation on NFκB signaling in human primary articular chondrocytes in comparison with the immortalized human costal chondrocyt...

In this study, oil was extracted from the liver and visceral fat of Patin (Pangasianodon hypophthalmus) and refined. The yield of oil after refining was 49.98%. The major yield loss (34.20%) happened during the degumming procedure. Fatty acids found in the crude and refined oil were C12:0, C14:0, C14:1, C16:0, C16:1, C18:0, C18:1, C18:2, C18:3, C18:4, C20:0, C20:1, C20:4, C20:5, and C22:6. The ...

The effect of synthetic sorbin derivatives was determined on cholera toxin-stimulated jejunal secretion in anesthetized rats in vivo, using both perfused and ligated loop. An inhibitory effect on water secretion induced by cholera toxin was shown with C-terminal sorbin peptides: C20 (YEPGKSSILQHERPVTKPQA-amide), C10 and Dala 7 heptapeptide-amide of sorbin, given by subcutaneous (SC) or intraduo...

A form of alpha-galactosylceramide, KRN7000, activates CD1d-restricted Valpha14-invariant (Valpha14i) natural killer (NK) T cells and initiates multiple downstream immune reactions. We report that substituting the C26:0 N-acyl chain of KRN7000 with shorter, unsaturated fatty acids modifies the outcome of Valpha14i NKT cell activation. One analogue containing a diunsaturated C20 fatty acid (C20:...

Background: The aim of the present study is the determination of the effects of seasonal variations on the proximate analysis, cholesterol content and fatty acid compositions of Helix aspersa. Materials and Methods: Garden snails (Helix aspersa) were picked up by hand from the Central Anatolia Region of Turkey, in autumn (November) and spring (April) in 2011. Fatty acid methyl esters (FAMEs) an...

BACKGROUND/AIM Clofarabine is transported into leukemic cells via the equilibrative nucleoside transporters (hENT) 1 and 2 and the concentrative nucleoside transporter (hCNT) 3, then phosphorylated by deoxycytidine kinase (dCK) and deoxyguanosine kinase (dGK) to an active triphosphate metabolite. Cytarabine uses hENT1 and dCK for its activation. We hypothesized that cytarabine-resistant leukemi...

The electronic correlations on a C20 molecule, as described by an extended Hubbard Hamiltonian with a nearest-neighbor Coulomb interaction of strength V , are studied using quantum Monte Carlo and exact diagonalization methods. For electron-doped C20, it is known that pair binding arising from a purely electronic mechanism is absent within the standard Hubbard model (V = 0). Here we show that t...

BACKGROUND Serum free fatty acids (FFAs) are correlated with pathological status, and change in serum FFA levels may be associated with thyroid diseases. MATERIALS AND METHODS In this study, 664 serum samples from 322 healthy controls, 129 patients with benign thyroid disease (BTD), and 213 patients with thyroid cancer (TC) were collected. Chip-based direct-infusion nanoelectrospray-mass spec...