OBJECTIVES To evaluate the effect of regular physical activity on metabolic risk factors and blood pressure in Inuit with high BMI consuming a western diet (high amount of saturated fatty acids and carbohydrates with a high glycemic index). STUDY DESIGN Cross sectional study, comparing Inuit eating a western diet with Inuit eating a traditional diet. METHODS Two physically active Greenland ...

BACKGROUND Cardiac hypertrophy is considered a necessary compensatory response to sustained elevations of left ventricular (LV) wall stress. METHODS AND RESULTS To test this, we inhibited calcineurin with cyclosporine (CsA) in the setting of surgically induced pressure overload in mice and examined in vivo parameters of ventricular volume and function using echocardiography. Normalized heart ...

The frequency weighting for assessing hand-transmitted vibration exposure is critical to obtaining a true dose-response relationship. Any valid weighting must have a solid theoretical foundation. The objectives of this study are to examine the biodynamic foundation for assessing the vibration exposure and to develop a set of biodynamic methods to formulate the frequency weightings for different...

Vol. 1: Immune Disorder. Ed. Leo van der Reis (San Francisco, Calif.) X + 188 p., 21 fig., 8 tab., 1975. ISBN 3-8055-1751-3 Vol. 2: Enzymology of the Liver. Ed. Leo van der Reis (San Francisco, Calif.) XIV + 296 p., 20 fig., 39 tab., 1976. ISBN 3-8055-2220-7 VoL 3: The Esophagus. Ed. Leo van der Reis (San Francisco, Calif.) X+ 166 p., 19 fig., 11 tab., 1978. ISBN 3-8055-2700-4 VoL 4: Gastrointe...

A simple surface-mounted tapered tab has recently attracted uids research both for its ability to enhance mixing and heat transfer (for which it is known as high-e ciency vortab mixer) and for its generation of coherent structures that are topologically similar to those found in natural turbulent boundary layers. Two types of structures, namely pressure-driven counter-rotating vortex pair (CVP)...

BACKGROUND The study aims to compare how work-to-rest ratio (W:R) influences insulin sensitivity (Si) and inflammatory responses following one session of sprint interval training (SIT). METHODS Thirteen men and two women completed a cross-over comparison of two SIT interventions-Tabata (TAB), 10 × 20-s sprints/10-s rest, and Wingate (WIN), 5 × 30-s sprints with 270-s rest. IL-6, IL-10, and TN...

BACKGROUND Earlier detection of transformed cells using target-specific imaging techniques holds great promise. We have developed TAB 004, a monoclonal antibody highly specific to a protein sequence accessible in the tumor form of MUC1 (tMUC1). We present data assessing both the specificity and sensitivity of TAB 004 in vitro and in genetically engineered mice in vivo. METHODS Polyoma Middle ...