in tropical and subtropical countries, envenomation by scorpions (so-called scorpionism) represents a serious public health problem. in the present study, the toxic effects of mice ld50 injections of mesobuthus eupeus (me) venom on the kidney and liver of anesthetized rabbits were investigated. six rabbits were selected and alt, ast, bun and creatinine were measured at 0, 1 and 3 hours after...

background: immunotherapy is the only specific treatment for scorpion envenomation. in the present study, the protective effects of polyvalent antivenom against histopathological complications in kidneys and marker changes (bun and creatinine) induced by mesobuthus eupeus (me) scorpion venom was investigated in anesthetized rabbits. methods: twenty four rabbits were randomized into four groups:...

introduction: scorpion venom is a source of bioactive peptides, and some antimicrobial peptides (amps) have been found in the venom gland of scorpions. therefore, the discovery of new anti-infective agents is an essential need to overcome the problem of antibiotic resistance of clinical isolates. here, we describe three new cationic amps, including meuvap-6, meuap-18-1, and meupep34 from the ve...

The biotopical distribution, size and age structure of the population, nocturnal activity rhythm feeding mottled scorpion (Mesobuthus eupeus) were studied. research was conducted on left bank Pirsagat river (Shirvan plain, Istern Azerbaijan). All discovered individuals scorpions divided into 5 groups by length metasome. distribution had a pronounced aggregated character with formation local clu...

Mikolaj Cieslak1,2,†, Alla N. Seleznyova2, Przemyslaw Prusinkiewicz3 and Jim Hanan4,* The University of Queensland, School of Mathematics and Physics, Qld 4072, Australia, The New Zealand Institute for Plant & Food Research Limited, Palmerston North 4442, New Zealand, Department of Computer Science, University of Calgary, AB T2N 1N4, Canada and The University of Queensland, Centre for Biologica...

Two dimensional (2D) NMR and molecular dynamics simulations have been used to determine the three dimensional (3D) structure of a hairpin DNA, d-CTA-GAGGATCC-TUTT-GGATCCT (22mer; abbreviated as U2-hairpin), which has uracil at the second position from the 5' end of the tetraloop. The(1)H resonances of this hairpin have been assigned almost completely. NMR restrained molecular dynamics and energ...