Abstract Background Early mechanisms underlying the progressive tissue death and regenerative capability of burn wounds are understudied in human skin. A clinically relevant, reproducible model for wound healing is needed to elucidate early changes environment. This study reports a contact on skin that explores extent injury over time, defines inter-individual variability enable use mechanistic...

background : burn wounds are one of the health problems in modern societies that are associated with irreparable harms and many side problems for patients and their families. infection due to burn wounds is the main cause of death in such patients. one of the methods to prevent infection of burn wounds is topical antibiotic ointments. this study aimed to investigate and identify effective ointm...

Severe burn injury is accompanied by a systemic inflammatory response, making traditional indicators of sepsis both insensitive and nonspecific. To address this, the American Burn Association (ABA) published diagnostic criteria in 2007 to standardize the definition of sepsis in these patients. These criteria include temperature (>39°C or <36°C), progressive tachycardia (>110 beats per minute), ...

The purpose of this study was to determine whether systemic inflammatory response syndrome (SIRS) and American Burn Association (ABA) criteria predict sepsis in the burn patient and develop a model representing the best combination of novel clinical sepsis predictors. A retrospective, case-controlled, within-patient comparison of burn patients admitted to a single intensive care unit from Janua...

Dear Editors, Burn injury can be fatal, disfiguring and incapacitating. Therefore, well-timed and appropriate management could be more than helpful, which primarily consists of debridement cleaning and dressings. These are important aspects of wound care because they can prevent the formation of eschar, which is a moist and protein-rich avascular substance that encourages microbial growth. Infe...

background self-inflicted burn injuries carry considerable mortality and morbidity among otherwise fit young individuals. this study assessed the epidemiologic pattern and outcome of these injuries in a burn care facility in pakistan. methods the study was carried out at pakistan institute of medical sciences (pims) burn care centre in islamabad over a period of 2 years. it included all adult p...

This study profiled intra-oral somatosensory and vasomotor responses to three different transient receptor potential (TRP) channels, subfamily A, member 1 (TRPA1) agonists (menthol, nicotine, and cinnamaldehyde) in smoking and non-smoking young adults. Healthy non-smokers (N = 30) and otherwise healthy smokers (N = 25) participated in a randomized, double-blinded, cross-over study consisting of...

The paper assesses spatio-temporal patterns of land surface temperature (LST) and fire severity in the Las Hurdes wildfire of Pinus pinaster forest, which occurred in July 2009, in Extremadura (Spain), from a time series of fifteen Landsat 5 TM images corresponding to 27 post-fire months. The differenced Normalized Burn Ratio (dNBR) was used to evaluate burn severity. The mono-window algorithm ...

A serious problem in emergency medicine is the correct evaluation of skin burn depth to make the appropriate choice of treatment. In clinical practice, there is no difficulty in classifying first- and third-degree burns correctly. However, differentiation between the IIa (superficial dermal) and IIb (deep dermal) wounds is problematic even for experienced practitioners. In this work, the use of...