Intact human skin surface is essential for protection against infection, preservation of body fluid homeostasis and thermoregulation. Burn injury compromises the skin barrier and enables bacterial infection, hence delaying burn wound healing. This study aimed to determine the microbial profile of burn wounds, and resistance patterns of microbes with respect to the source of the injured patient'...

Burned patients are at risk of acquiring infection because of their destroyed skin barrier, suppression of immunity, prolonged hospitalization, and invasive therapeutic and diagnostic procedures. Most of the studies on infections in burned patients are focused on burn wound infections, while nosocomial device-associated infections in this patient group are not described well. Therefore, the aim...

conclusions non-albicans candida should be considered as significant pathogens in burned patients with candidemia. results twenty-seven samples (6.7%) of the blood cultures from 13 patients (12%) were positive for candida species. candida parapsilosis (38%) and c. tropicalis (38%) were the most commonly found candida species, followed by c. albicans (15%) and c. guilliermondii (15%) in the pati...

introduction and aims: acinetobacter baumannii in recent decay has become an increasing concern in hospitals for its ability to acquire antibiotic resistance determinants rapidly and becoming resistant to almost all of the antibiotic classes. borage (echium amoenum  fisch. et mey), is a wild annual plant of boraginaceae family, grows in northern mountains of iran and has largely been used by ir...

BACKGROUND Acinetobacter calcoaceticus-baumannii complex (Acb) is recognized as an important cause of nosocomial infections. Although Acb can be associated with multidrug resistance, its impact on mortality in burn patients has not been fully elucidated. STUDY DESIGN In a retrospective cohort study assessing medical records and microbiology laboratory data at a US military tertiary care burn ...

Burn patients are highly susceptible to infections due to increased exposure through wounds and impairments in a number of immune functions. Dendritic cells (DCs) are important in activation of numerous immune responses that are essential for the clearance of infections. We have found that prophylactic treatment of burn-injured mice with the DC growth factor FLT3 ligand (FL) significantly incre...

Most mild burns may be treated well in an outpatient environment and recover with little intervention. An precise categorization of is essential to ensuring effective treatment. Any non-superficial burn should a topical antibiotic avoid infection. Although partial full-thickness frequently require dressings, superficial typically do not. Especially emergency situation, simple gauze patch offers...

BACKGROUND Pseudomonas aeruginosa remains a leading cause of severe wound infection and mortality in burn patients. OBJECTIVES The current study aimed to determine the prevalence of Ambler class A and D β-lactamases among P. aeruginosa isolated from infected burn injuries in Tehran, Iran. PATIENTS AND METHODS Bacteriological samples were taken from burn patients with clinical symptoms of bu...