Scrub typhus occurs in almost all parts of India and is endemic1. Many researchers have reported the profile of scrub typhus from various parts of India with diagnosis based on IgM ELISA2-4. Eschar is pathognomonic for rickettsiosis including scrub typhus, but its presence has not been reported as a marker of disease severity. Kim et al5 found absence of eschar to have prognostic significance i...

t first glance, the baby appeared healthy. She was pudgy, pink-cheeked and impeccably clean, and rested quietly in the mother’s arms—until we disturbed her; then she cried with the weary wail of an infant hurting for days. “This one came first,” said the mother, pointing to a quarter-sized red, swollen nodule to the right of the baby’s spine. Embedded in its center was a jet-black eschar the si...

Bacteria genetically related to Coxiella burnetii have been found in ticks. Using molecular techniques, we detected Coxiella-like bacteria, here named Candidatus Coxiella massiliensis, in skin biopsy samples and ticks removed from patients with an eschar. This organism may be a common agent of scalp eschar and neck lymphadenopathy after tick bite.

We describe a man with a febrile illness and an eschar that developed at the site of a tick bite. Rickettsia parkeri was detected and isolated from the eschar. This report represents the second documented case of R. parkeri rickettsiosis in a US serviceman in eastern Virginia.

Scrub typhus is a common and underdiagnosed cause of febrile illness in Southeast Asia, caused by infection with Orientia tsutsugamushi. Inoculation of the organism at a cutaneous mite bite site commonly results in formation of a localized pathological skin reaction termed an eschar. The site of development of the obligate intracellular bacteria within the eschar and the mechanisms of dissemina...

We report the first laboratory-confirmed case of Rickettsia mongolotimonae infection in Africa. The patient sought treatment for an eschar on his toe; lymphangitis, severe headaches, and fever subsequently developed. After a regimen of doxycycline, symptoms rapidly resolved. R. mongolotimonae infection was diagnosed retrospectively by serologic tests and molecular-based detection of the organis...

Four children, from 5 to 10 years aged, presented the Sylvanus Olympio Hospital (SOTH) of Lomé (Togo) with severe (second- and third-degree) burns 25–78% total body surface area (TBSA) due flame in domestic accidents were treated using skin substitutes. We conducted substitution by dermal templates (Integra®) for two children allografts other two. In cases templates, we performed a wound excisi...

Abstract Introduction Outside the United States, bromelain-based enzymatic debridement (BBED) has become an effective tool for removal of burn eschar. BBED can be performed at bedside and allows complete eschar with maximal dermal preservation markedly reduced blood loss. It may also decrease need autografting or amount autograft required. A primary concern is that it a painful procedure requir...