Alzheimer's disease (AD) and osteoporosis are both common degenerative diseases in the elderly population. The incidence of both diseases increases with age and will be posing enormous societal burden worldwide. It may appear that AD and osteoporosis are two distinct diseases although many risk factors are shared. Previous observational studies have shown that patients with osteoporosis have hi...

according to importance of cirrhosis of the liver and the lack of information about the economic burden of the disease, we performed this study to estimate the economic burden of liver cirrhosis in iran in 2011.the cost-of-illness method, based on the human capital theory, has been used. both direct and indirect costs have been estimated using a prevalence approach and bottom-up method. the inp...

introduction: disabled-adjusted life year (daly) makes it possible to calculate the time and duration of the disease and its non-fatal consequences along with the time lost due to premature death. this study was aimed to estimate the burden of road traffic accidents (rta) in kermanshah province. methods: to determine the mortality related to road-traffic accidents as well as years of life lost ...

Osteoporosis is a complex multifactorial bone disorder with a strong genetic basis. It is the most common, severe, progressive skeletal illness that has been increasing, particularly in developed countries. Osteoporosis will no doubt constitute a serious clinical burden in healthcare management in the coming decades. The genetics of osteoporosis should be analyzed from both the disease suscepti...

Postmenopausal osteoporosis is an asymptomatic skeletal disease that is often underdiagnosed and undertreated. Osteoporotic fractures are associated with substantial morbidity and mortality and impaired quality of life-socially, emotionally, and financially. Considering the growing burden of osteoporotic fractures worldwide, there remains an ongoing need for progress in the diagnosis of osteopo...

Until the 1940s, when Albright associated osteoporosis with a defect of bone anabolism, it was not considered a disease entity but an inevitable consequence of the ageing process for which there was little remedy.1 Bisphosphonates, fi rst synthesised in the 1800s but in clinical use only since the 1960s, demonstrated that this process of age-related decline in bone was, in fact, modifi able.2 M...

Osteoporosis has a complex etiology and is considered a multifactorial polygenic disease, in which genetic determinants are modulated by hormonal, lifestyle, environmental, and nutritional factors. Therefore, investigating these multiple factors, and the interactions between them, might lead to a better understanding of osteoporosis pathogenesis, and possible therapeutic interventions. The obje...

Osteoporosis -related to various factors including menopause and aging- is the most common chronic metabolic bone disease, which is characterized by increased bone fragility. Although it is seen in all age groups, gender, and races, it is more common in Caucasians (white race), older people, and women. With an aging population and longer life span, osteoporosis is increasingly becoming a global...

conclusions it seems that nasal spray of calcitonin can effectively improve qol of women with lbd and qol changes were not influenced by clinical or para-clinical alteration. mental health domain must be more considered in further studies as a predicting domain for health-related quality of life (hr-qol) changes. background physical activity and mental health could be affected by osteoporosis a...